SCHEMBL2454575

SCHEMBL2454575

CCCC[SiH2]OS(=O)(=O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.36
FAAH O00519 5/20 0.30
CES1 P23141 5/20 0.30
CES2 O00748 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6606387 0.94 EPHX1 (0.39) EPHX1FAAHCES1CES2
SCHEMBL6552562 0.88 EPHX1 (0.31) EPHX1
SCHEMBL4435018 0.79
SCHEMBL777643 0.68 CA2 (0.52) EPHX1CES2
SCHEMBL28169619 0.68
SCHEMBL38550 0.67 CA1 (0.54) EPHX1FAAHCES1CES2
SCHEMBL28408544 0.67 F2 (0.31)
SCHEMBL29170929 0.67 CA1 (0.50) EPHX1CES2
SCHEMBL27930318 0.67 CA1 (0.50) EPHX1CES2
SCHEMBL27912318 0.67 CA1 (0.50) EPHX1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020162393-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND 日産化学株式会社 2020-08-13 WO disclosed
WO-2011109276-A8 EPOXIDATION CATALYSTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-10-13 WO disclosed
WO-2011109276-A1 EPOXIDATION CATALYSTS MASSACHUSSETS INSTITUTE OF TECHNOLOGY (US) 2011-09-09 WO disclosed