SCHEMBL4435018

SCHEMBL4435018

CC[SiH2]OS(=O)(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6552562 0.82 EPHX1 (0.31)
SCHEMBL2454575 0.79 EPHX1 (0.36)
SCHEMBL6606387 0.77 EPHX1 (0.39)
SCHEMBL28169619 0.74
SCHEMBL6686763 0.73
SCHEMBL28408544 0.73 F2 (0.31)
SCHEMBL9027632 0.73 CA2 (0.36)
SCHEMBL2904316 0.72 CA1 (0.38)
SCHEMBL9027630 0.71
SCHEMBL5155693 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023142618-A1 SYNTHESIS METHOD FOR EUPHORBIA DITERPENOID PEPLUANOL A 浙江大学杭州国际科创中心 2023-08-03 WO claimed
JP-5345794-A None JP disclosed
WO-2022256490-A9 IMPROVED SYNTHESIS OF PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS Antios Therapeutics, Inc. (US) 2023-08-17 WO disclosed
US-8314246-B2 Catalytic reactions involving alkenes MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-11-20 US disclosed
US-20090216025-A1 Catalytic reactions involving alkenes MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-08-27 US disclosed
WO-2007027752-A1 CATALYTIC REACTIONS INVOLVING ALKENES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-03-08 WO disclosed
EP-1749001-A1 3-PIPERIDINYLISOCHROMAN-5-OLS AS DOPAMINE AGONISTS Aventis Pharmaceuticals, Inc. (US) 2007-02-07 EP disclosed
US-7173137-B2 Epothilone analogs THE SCRIPPS RESEARCH INSTITUTE (US) 2007-02-06 US disclosed
WO-2005111025-A1 3-PIPERIDINYLISOCHROMAN-5-OLS AS DOPAMINE AGONISTS AVENTIS PHARMACEUTICALS INC. (US) 2005-11-24 WO disclosed
US-20040127432-A1 Epothilone analogs THE SCRIPPS RESEARCH INSTITUTE 2004-07-01 US disclosed
WO-1995009175-A1 RING-EXPANDED NUCLEOSIDES AND NUCLEOTIDES BURNS BARRY (US) 1995-04-06 WO disclosed
WO-1995008557-A1 NOVEL OLIGOSACCHARIDE-CONTAINING 14-AMINOSTEROID COMPOUNDS AND NOVEL DIASTEREOSELECTIVE AMINOSTEROID PROCESS CHEMISTRY THE PROCTER & GAMBLE COMPANY (US) 1995-03-30 WO disclosed
EP-0642345-A1 HALICHONDRINS AND RELATED COMPOUNDS THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1995-03-15 EP disclosed
JP-H05345794-A PRODUCTION OF GLYCOSYLANTHRACYCLINONES BEHRINGWERKE AG 1993-12-27 JP disclosed
EP-0562009-A4 ENANTIOMERICALLY PURE -G(B)-D-(-)-DIOXOLANE-NUCLEOSIDES 1993-11-24 EP disclosed
EP-0562009-A1 ENANTIOMERICALLY PURE $g(b)-D-(-)-DIOXOLANE-NUCLEOSIDES THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1993-09-29 EP disclosed
EP-0560794-A1 SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES. IAF BIOCHEM INT (CA) 1993-09-22 EP disclosed
WO-1993017690-A1 HALICHONDRINS AND RELATED COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1993-09-16 WO disclosed
WO-1993000908-A1 ELAM-1 RECEPTOR LIGANDS AS DIAGNOSTIC COMPOUNDS ANTISOMA LIMITED (GB) 1993-01-21 WO disclosed
WO-1992010497-A1 ENANTIOMERICALLY PURE β-D-(-)-DIOXOLANE-NUCLEOSIDES UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1992-06-25 WO disclosed