Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24547629 | 0.89 | LMNA (0.46) | SMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL24547598 | 0.86 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAALDH1A1POLBABL1 | |
| SCHEMBL24547602 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1POLBABL1 | |
| SCHEMBL24547472 | 0.83 | DNMT1 (0.42) | SMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL24584519 | 0.83 | LMNA (0.58) | SMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL24583370 | 0.83 | LMNA (0.58) | SMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL24547604 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAALDH1A1POLBABL1 | |
| SCHEMBL24547500 | 0.82 | ABL1 (0.45) | SMN1; SMN2LMNAALDH1A1POLBKMT2A | |
| SCHEMBL24547475 | 0.82 | ABL1 (0.45) | SMN1; SMN2LMNAALDH1A1POLBKMT2A | |
| SCHEMBL29637590 | 0.70 | SMN1; SMN2 (0.35) | SMN1; SMN2LMNAALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133323-A1 | 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS | SOUTHERN RESEARCH INSTITUTE (US) | 2022-06-23 | — | — | WO | disclosed |