Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 9/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24547604 | 0.96 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAPOLBALDH1A1HPGD | |
| SCHEMBL24547598 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAPOLBALDH1A1ABL1 | |
| SCHEMBL24547603 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAPOLBALDH1A1HPGD | |
| SCHEMBL24584241 | 0.82 | LMNA (0.62) | SMN1; SMN2LMNAPOLBALDH1A1ADORA2A | |
| SCHEMBL24547599 | 0.81 | DNMT1 (0.45) | SMN1; SMN2LMNAPOLBALDH1A1DYRK1A | |
| SCHEMBL24547564 | 0.80 | ABL1 (0.49) | SMN1; SMN2LMNAPOLBALDH1A1HPGD | |
| SCHEMBL24547620 | 0.80 | ABL1 (0.49) | SMN1; SMN2LMNAPOLBALDH1A1HPGD | |
| SCHEMBL24547629 | 0.79 | LMNA (0.46) | SMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL24547600 | 0.78 | LMNA (0.60) | SMN1; SMN2LMNAPOLBALDH1A1ADORA2A | |
| SCHEMBL24547645 | 0.77 | DNMT1 (0.43) | SMN1; SMN2LMNAPOLBALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133323-A1 | 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS | SOUTHERN RESEARCH INSTITUTE (US) | 2022-06-23 | — | — | WO | disclosed |