Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | WNT1 | P04628 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24547564 | 1.00 | ABL1 (0.49) | ABL1RIN1HPGDALDH1A1LMNA | |
| SCHEMBL24547646 | 0.95 | ABL1 (0.47) | ABL1RIN1HPGDALDH1A1LMNA | |
| SCHEMBL24547566 | 0.84 | ABL1 (0.46) | ABL1RIN1ALDH1A1LMNAPOLB | |
| SCHEMBL24547640 | 0.84 | ABL1 (0.46) | ABL1RIN1ALDH1A1LMNAPOLB | |
| SCHEMBL24547500 | 0.83 | ABL1 (0.45) | ABL1RIN1HPGDALDH1A1LMNA | |
| SCHEMBL24547475 | 0.83 | ABL1 (0.45) | ABL1RIN1HPGDALDH1A1LMNA | |
| SCHEMBL24547599 | 0.81 | DNMT1 (0.45) | ALDH1A1LMNAPOLBSMN1; SMN2DYRK1A | |
| SCHEMBL17591088 | 0.81 | ABL1 (0.45) | ABL1RIN1ALDH1A1LMNAPOLB | |
| SCHEMBL19215382 | 0.81 | ABL1 (0.45) | ABL1RIN1ALDH1A1LMNAPOLB | |
| SCHEMBL24547602 | 0.80 | SMN1; SMN2 (0.40) | ABL1RIN1HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133323-A1 | 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS | SOUTHERN RESEARCH INSTITUTE (US) | 2022-06-23 | — | — | WO | disclosed |