Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24547566 | 1.00 | ABL1 (0.46) | ABL1RIN1MAPTCCNA2CDK2 | |
| SCHEMBL24547620 | 0.84 | ABL1 (0.49) | ABL1RIN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24547564 | 0.84 | ABL1 (0.49) | ABL1RIN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24547475 | 0.83 | ABL1 (0.45) | ABL1RIN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24547500 | 0.83 | ABL1 (0.45) | ABL1RIN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10482526 | 0.83 | ABL1 (0.68) | ABL1RIN1MAPTCCNA2CDK2 | |
| SCHEMBL24547646 | 0.82 | ABL1 (0.47) | ABL1RIN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24547505 | 0.81 | LMNA (0.42) | ABL1RIN1MAPTALDH1A1LMNA | |
| SCHEMBL24547644 | 0.81 | LMNA (0.42) | ABL1RIN1MAPTALDH1A1LMNA | |
| SCHEMBL24547598 | 0.81 | SMN1; SMN2 (0.38) | ABL1RIN1MAPTCCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133323-A1 | 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS | SOUTHERN RESEARCH INSTITUTE (US) | 2022-06-23 | — | — | WO | disclosed |