SCHEMBL24547741

SCHEMBL24547741

COc1ccc(C(=O)n2c3ccccc3c3c2cnn3C)cc1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.49
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 2/20 0.46
MGAM O43451 1/20 0.46
F12 P00748 1/20 0.46
AMY1A P0DUB6 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24547742 0.87 P2RX4 (0.56) LMNAMAPTHTTKMT2AGAA
SCHEMBL24547736 0.87 ELANE (0.52)
SCHEMBL24547658 0.86 LMNA (0.67) LMNAMAPTHTTKMT2A
SCHEMBL24547661 0.85 ABCB1 (0.50) LMNAMAPTHTTKMT2AF12
SCHEMBL24547737 0.85 LMNA (0.50) LMNAMAPTHTTKMT2AMGAM
SCHEMBL24547630 0.84 LMNA (0.48) LMNAMAPTHTTKMT2AGAA
SCHEMBL24547738 0.81 HTT (0.48) CNR2LMNAMAPTHTTMGAM
SCHEMBL24547657 0.80 LMNA (0.44) LMNAMAPTHTTKMT2AMGAM
SCHEMBL24547632 0.79 P2RX4 (0.43) LMNAMAPTHTTKMT2AGAA
SCHEMBL24547744 0.76 KDM4E (0.45) LMNAMAPTHTTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS Kinoxis Therapeutics Pty Ltd (AU) 2024-02-29 US disclosed
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS Kinoxis Therapeutics Pty Ltd (AU) 2024-02-29 US disclosed
WO-2022126179-A1 OXYTOCIN RECEPTOR MODULATORS THE UNIVERSITY OF SYDNEY (AU) 2022-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS OXTR, AVPR1B, AVPR1A CNR2 234/4885LMNA 2876/4885MAPT 380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.