Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 16/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 11/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | FRK | P42685 | 1/20 | 0.47 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24547941 | 0.84 | CSNK1D (0.52) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 | |
| SCHEMBL24547958 | 0.84 | CSNK1D (0.52) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 | |
| SCHEMBL24548191 | 0.82 | CSNK1D (0.53) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 | |
| SCHEMBL24547942 | 0.82 | CSNK1D (0.50) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 | |
| SCHEMBL29089545 | 0.80 | CSNK1D (0.47) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 | |
| SCHEMBL24547932 | 0.76 | CSNK1D (0.50) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 | |
| SCHEMBL24548201 | 0.75 | CSNK1D (0.54) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 | |
| SCHEMBL24547950 | 0.74 | CSNK1D (0.53) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 | |
| SCHEMBL24548188 | 0.72 | CSNK1D (0.53) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 | |
| SCHEMBL9932804 | 0.72 | CSNK1D (0.63) | CSNK1DMAPK14MAPK11CSNK1EMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250275965-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) | 2025-09-04 | — | — | US | disclosed |
| CN-116888126-A | Compound of casein kinase inhibitor | 北京原基华毅生物科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| WO-2022127755-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022127755-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2022-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250275965-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | PACSIN2, CSNK1A1, CSNK1G3 | CSNK1D 12/4885MAPK14 210/4885MAPK11 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.