SCHEMBL24548191

SCHEMBL24548191

Cn1cc(-c2ccnn3c(NC(=O)C4CC4)cnc23)c(-c2ccc(F)cc2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1D P48730 18/20 0.53
CSNK1E P49674 15/20 0.53
MAPK14 Q16539 6/20 0.45
MAPK11 Q15759 4/20 0.45
MAPK13 O15264 2/20 0.43
MAPK12 P53778 2/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43
ADORA1 P30542 1/20 0.43
GSK3B P49841 2/20 0.43
NUAK1 O60285 1/20 0.43
ROCK2 O75116 1/20 0.43
MAP4K4 O95819 1/20 0.43
LCK P06239 1/20 0.43
MAPK8 P45983 1/20 0.43
MAPK9 P45984 1/20 0.43
CSNK1A1 P48729 1/20 0.43
MAP2K1 Q02750 1/20 0.43
MINK1 Q8N4C8 1/20 0.43
AURKB Q96GD4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24548007 0.82 CSNK1D (0.53) CSNK1DCSNK1EMAPK14MAPK11MAPK13
SCHEMBL24547941 0.76 CSNK1D (0.52) CSNK1DCSNK1EMAPK14MAPK11MAPK13
SCHEMBL24547958 0.76 CSNK1D (0.52) CSNK1DCSNK1EMAPK14MAPK11MAPK13
SCHEMBL24547942 0.74 CSNK1D (0.50) CSNK1DCSNK1EMAPK14MAPK11MAPK13
SCHEMBL29089545 0.74 CSNK1D (0.47) CSNK1DCSNK1EMAPK14MAPK11MAPK13
SCHEMBL16105637 0.72 CSNK1D (0.62) CSNK1DCSNK1EMAPK14MAPK11MAPK13
SCHEMBL9933198 0.70 CSNK1D (0.56) CSNK1DCSNK1EMAPK14MAPK11MAPK13
SCHEMBL24548209 0.70 CSNK1D (0.44) CSNK1DCSNK1EMAPK14MAPK11MAPK13
SCHEMBL24547930 0.69 CSNK1D (0.54) CSNK1DCSNK1E
SCHEMBL24548187 0.69 CSNK1D (0.47) CSNK1DCSNK1EMAPK14MAPK11MAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250275965-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) 2025-09-04 US disclosed
WO-2022127755-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS Gritscience Biopharmaceuticals Co., Ltd. (CN) 2022-06-23 WO disclosed
WO-2022127755-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS Gritscience Biopharmaceuticals Co., Ltd. (CN) 2022-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250275965-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS PACSIN2, CSNK1A1, CSNK1G3 CSNK1D 12/4885CSNK1E 9/4885MAPK14 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.