Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.69 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.69 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.69 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.53 |
| ▸ | KDM5C | P41229 | 3/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.50 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL7619170 | 0.88 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL18604000 | 0.88 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Adipic Acid SCHEMBL11647911 | 0.86 | LMNA (0.73) | LMNAGABRR1SLC22A6TSHRHDAC3 | |
| Succinic Acid SCHEMBL28141690 | 0.85 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL28141692 | 0.85 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL27804789 | 0.84 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL28156291 | 0.84 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL7752977 | 0.84 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL28729193 | 0.84 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL1655131 | 0.84 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691120-A | PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1997-11-25 | — | — | US | claimed |
| US-5652085-A | BLEACHING/FIXING PHOTOGRAPHIC FILMS | EASTMAN KODAK COMPANY (US) | 1997-07-29 | — | — | US | claimed |
| US-10448515-B2 | Method for reducing the optical reflectivity of a copper and copper alloy circuitry and touch screen device | ATOTECH DEUTSCHLAND GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| EP-3180457-B1 | METHOD FOR REDUCING THE OPTICAL REFLECTIVITY OF A COPPER AND COPPER ALLOY CIRCUITRY AND TOUCH SCREEN DEVICE | ATOTECH DEUTSCHLAND GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |
| EP-3049549-B1 | METHOD FOR TREATMENT OF RECESSED STRUCTURES IN DIELECTRIC MATERIALS FOR SMEAR REMOVAL | ATOTECH DEUTSCHLAND GMBH (DE) | 2019-03-20 | — | — | EP | disclosed |
| US-20170245372-A1 | METHOD FOR REDUCING THE OPTICAL REFLECTIVITY OF A COPPER AND COPPER ALLOY CIRCUITRY AND TOUCH SCREEN DEVICE | ATOTECH USA, LLC | 2017-08-24 | — | — | US | disclosed |
| EP-3180457-A1 | METHOD FOR REDUCING THE OPTICAL REFLECTIVITY OF A COPPER AND COPPER ALLOY CIRCUITRY AND TOUCH SCREEN DEVICE | ATOTECH Deutschland GmbH (DE) | 2017-06-21 | — | — | EP | disclosed |
| US-9650718-B2 | Electroless copper plating solution | ATOTECH DEUTSCHLAND GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| EP-3049549-A1 | METHOD FOR TREATMENT OF RECESSED STRUCTURES IN DIELECTRIC MATERIALS FOR SMEAR REMOVAL | ATOTECH Deutschland GmbH (DE) | 2016-08-03 | — | — | EP | disclosed |
| US-20160205783-A1 | METHOD FOR TREATMENT OF RECESSED STRUCTURES IN DIELECTRIC MATERIALS FOR SMEAR REMOVAL | ATOTECH USA, LLC | 2016-07-14 | — | — | US | disclosed |
| US-20160053379-A1 | ELECTROLESS COPPER PLATING SOLUTION | ATOTECH DEUTSCHLAND GMBH & CO. KG (F/K/A ATOTECH DEUTSCHLAND GMBH) (DE) | 2016-02-25 | — | — | US | disclosed |
| EP-0762203-B1 | Succinic acid derivative degradable chelants, uses and compositions thereof | EASTMAN KODAK CO (US) | 2002-10-16 | — | — | EP | disclosed |
| EP-0850293-B1 | SUCCINIC ACID DERIVATIVE DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | DOW CHEMICAL CO (US) | 2001-10-17 | — | — | EP | disclosed |
| US-5846925-A | Succinic acid derivative degradable chelants, uses and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0850293-A1 | SUCCINIC ACID DERIVATIVE DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1998-07-01 | — | — | EP | disclosed |
| US-5733858-A | LAUNDRY DETERGENTS | THE DOW CHEMICAL COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| US-5691120-A | PHOTOGRAPHY | EASTMAN KODAK COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| US-5652085-A | BLEACHING/FIXING PHOTOGRAPHIC FILMS | EASTMAN KODAK COMPANY (US) | 1997-07-29 | — | — | US | disclosed |
| EP-0762203-A1 | Succinic acid derivative degradable chelants, uses and compositions thereof | EASTMAN KODAK COMPANY (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1997008288-A1 | SUCCINIC ACID DERIVATIVE DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1997-03-06 | — | — | WO | disclosed |