Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.82 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.82 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.82 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.82 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.56 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KDM5C | P41229 | 2/20 | 0.56 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.56 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28729193 | 1.00 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL7528388 | 0.96 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL1655131 | 0.91 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL27804789 | 0.91 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL28156291 | 0.91 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL1237233 | 0.91 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL829 | 0.91 | — | — | |
| Succinic Acid SCHEMBL4269130 | 0.91 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL3799615 | 0.91 | — | — | |
| Succinic Acid SCHEMBL21867134 | 0.91 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106731506-B | Efficient, long-acting formaldehyde eliminating agent of one kind and preparation method thereof | 浙江蓝山环保科技有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110072560-A | For the method using compound label sensitivity and thermal sensitivity targeting biological molecules based on technetium | 伯拉考成像股份公司 | 2019-07-30 | — | — | CN | claimed |
| CN-109173643-A | A kind of plant source extraction bactericidal deodorant and preparation method thereof for dispelling formaldehyde | 北京弘纳绿源科技发展有限公司 | 2019-01-11 | — | — | CN | claimed |
| CN-105176647-B | A kind of wire cutting oil and preparation method thereof | 苏州市晶协高新电子材料有限公司 | 2018-01-09 | — | — | CN | claimed |
| CN-106731506-A | A kind of efficient, long-acting formaldehyde eliminating agent and preparation method thereof | 杭州蓝山环保科技有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-1829683-A | Mildronate, preparation method thereof and pharmaceutical composition based on mildronate | GRINDEKS JSC (LV) | 2006-09-06 | — | — | CN | claimed |
| CN-110431184-A | Bridging property rubber composition and rubber cross object | ZEON CORP | 2019-11-08 | — | — | CN | disclosed |
| CN-106731506-B | Efficient, long-acting formaldehyde eliminating agent of one kind and preparation method thereof | 浙江蓝山环保科技有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-107076909-B | Unilateral side protection polarizing coating, the polarizing coating with adhesive phase, image display device and its method for continuous production | 日东电工株式会社 | 2019-09-17 | — | — | CN | disclosed |
| CN-110139887-A | The manufacturing method of polyether polyol and the manufacturing method of polyurethane foam | 三洋化成工业株式会社 | 2019-08-16 | — | — | CN | disclosed |
| CN-107076910-B | Unilateral side protection polarizing coating, the polarizing coating with adhesive phase, image display device and its method for continuous production | 日东电工株式会社 | 2019-08-06 | — | — | CN | disclosed |
| CN-110088154-A | Nitrile rubber containing carboxyl and its manufacturing method, Cross-linkable nitrile rubber composition and rubber cross object | 日本瑞翁株式会社 | 2019-08-02 | — | — | CN | disclosed |
| CN-106795333-B | Crosslinkable nitrile rubber composition and crosslinked rubber | 日本瑞翁株式会社 | 2019-07-02 | — | — | CN | disclosed |
| CN-106457954-A | Stabilizer bar with rubber bush and method for producing same | 日本发条株式会社 | 2017-02-22 | — | — | CN | disclosed |
| CN-1829683-B | Mildronate, preparation method thereof and pharmaceutical composition based on mildronate | UNION GREEN DAS | 2010-05-12 | — | — | CN | disclosed |
| CN-100513486-C | Emulsion and coating liquid and recording medium using the same | ASAHI CHEMICAL IND (JP) | 2009-07-15 | — | — | CN | disclosed |
| CN-1829683-A | Mildronate, preparation method thereof and pharmaceutical composition based on mildronate | GRINDEKS JSC (LV) | 2006-09-06 | — | — | CN | disclosed |
| CN-1503736-A | Emulsion and coating liquid and recording medium using the same | ������������ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| WO-2001045745-A2 | A REVERSIBLE LINKAGE TECHNOLOGY FOR CONTROLLED CONJUGATION | ACAMBIS RESEARCH LIMITED (GB) | 2001-06-28 | — | — | WO | disclosed |
| US-4062684-A | ANTIFOGGING, NITROGEN HETEROCYCLE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |