Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.78 |
| ▸ | NPC1 | O15118 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415002 | 0.89 | RAB9A (0.97) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL1415071 | 0.88 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL1415226 | 0.88 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL24549816 | 0.86 | RAB9A (0.80) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL1415022 | 0.86 | ALDH1A1 (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL1415096 | 0.86 | ALDH1A1 (0.84) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL1415033 | 0.85 | RAB9A (0.78) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL24549823 | 0.85 | RAB9A (0.78) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL7977556 | 0.85 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL2020664 | 0.82 | SMN1; SMN2 (0.69) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129256-A1 | SELECTIVE HDAC6 INHIBITOR | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2022-06-23 | — | — | WO | disclosed |