SCHEMBL2455366

SCHEMBL2455366

CCCCCC(C(=O)O)c1ccc(/N=N/c2ccc(OCC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
POLB P06746 2/20 0.50
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPK1 P28482 2/20 0.46
MAPT P10636 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46
ALDH1A1 P00352 1/20 0.45
CYP1A2 P05177 1/20 0.45
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
GAA P10253 1/20 0.41
HTT P42858 1/20 0.41
GPR88 Q9GZN0 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
SLC2A1 P11166 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2455368 1.00 LMNA (0.52) LMNAPOLBTDP1L3MBTL1MAPK1
SCHEMBL11674599 0.96 LMNA (0.50) LMNAPOLBTDP1L3MBTL1MAPK1
SCHEMBL11674588 0.96 LMNA (0.50) LMNAPOLBTDP1L3MBTL1MAPK1
SCHEMBL27572432 0.91 LMNA (0.61) LMNAPOLBTDP1L3MBTL1MAPK1
SCHEMBL964045 0.84 POLB (0.51) LMNAPOLBTDP1L3MBTL1MAPT
SCHEMBL20495545 0.82 LMNA (0.73) LMNAPOLBTDP1L3MBTL1MMP9
SCHEMBL11680096 0.81 SMN1; SMN2 (0.43) LMNATDP1MAPTMMP9MMP8
SCHEMBL28414792 0.80 HSD17B3 (0.47) LMNAPOLB
SCHEMBL28413265 0.79 HSD17B3 (0.47) LMNAPOLB
SCHEMBL28305005 0.77 CTRC (0.60) LMNAPOLBMMP9MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
US-20170336663-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2017-11-23 US disclosed
EP-3215587-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF Gauzy Ltd. (IL) 2017-09-13 EP disclosed
EP-3209748-A1 METAL ORGANIC LIQUID CRYSTAL DYES Gauzy Ltd (IL) 2017-08-30 EP disclosed
WO-2011123457-A1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2011-10-06 WO disclosed
US-20110234944-A1 Polymer-stabilized thermotropic liquid crystal device RAVENBRICK LLC (US) 2011-09-29 US disclosed
EP-1372023-A2 Electro-optically concealable vehicle instrument panel and method of constructing the same Ergom Automotive S.p.a. (IT) 2003-12-17 EP disclosed
US-6049366-A PLACING A LIQUID CRYSTAL FLUID COMPRISING LIQUID CRYSTAL, A PREPOLYMER, AND MICROPARTICLES BETWEEN FLEXIBLE CONDUCTIVE SUBSTRATES; LAMINATING THE SUBSTRATE TOGETHER, CURING THE FLUID LIQUID CRYSTAL COMPRISING THE PREPOLYMER SNIARICERCHE S.C.P.A. (IT) 2000-04-11 US disclosed
EP-0656927-B1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S C P A (IT) 1999-12-01 EP disclosed
EP-0927753-A1 Liquid crystal dispersed polymer electrooptical films having reverse morphology Sniaricerche S.C.P.A. (IT) 1999-07-07 EP disclosed
US-5843333-A Metallo organo liquid crystals in a polymer matrix SNIARICERCHE S.C.P.A (IT) 1998-12-01 US disclosed
EP-0787782-A2 Process and materials for highly transparent polymer dispersed liquid crystals Sniaricerche S.C.P.A. (IT) 1997-08-06 EP disclosed
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 EP disclosed
WO-1995001410-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S.C.P.A. (IT) 1995-01-12 WO disclosed