Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29683070 | 1.00 | MAPK14 (0.49) | MAPK14CSNK1DRIPK3NR3C2GSK3B | |
| SCHEMBL24554288 | 0.93 | RIPK3 (0.46) | MAPK14CSNK1DRIPK3NR3C2GSK3B | |
| SCHEMBL29683094 | 0.93 | NR3C2 (0.46) | MAPK14CSNK1DNR3C2GSK3BMAPK10 | |
| SCHEMBL24554207 | 0.93 | NR3C2 (0.46) | MAPK14CSNK1DNR3C2GSK3BMAPK10 | |
| SCHEMBL29683284 | 0.91 | MAPK14 (0.43) | MAPK14CSNK1DRIPK3NR3C2GSK3B | |
| SCHEMBL24553836 | 0.91 | MAPK14 (0.43) | MAPK14CSNK1DRIPK3NR3C2GSK3B | |
| SCHEMBL29683167 | 0.91 | MAPK14 (0.56) | MAPK14CSNK1DNR3C2GSK3B | |
| SCHEMBL24553788 | 0.91 | MAPK14 (0.56) | MAPK14CSNK1DNR3C2GSK3B | |
| SCHEMBL24553781 | 0.90 | MAPK14 (0.46) | MAPK14CSNK1DNR3C2GSK3B | |
| SCHEMBL24553697 | 0.90 | MAPK14 (0.53) | MAPK14CSNK1DMAPK10MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127756-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2022-06-23 | — | — | WO | disclosed |