SCHEMBL29683167

SCHEMBL29683167

CN1CCn2nc(-c3ccc(F)cc3)c(-c3ccnc(NC(=O)Cc4ccc(F)cc4)c3)c2C1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MAPK14 Q16539 14/20 0.56
▸ CSNK1D P48730 1/20 0.56
▸ WNT3A P56704 2/20 0.47
▸ GSK3B P49841 4/20 0.46
▸ MEN1 O00255 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ NR3C2 P08235 1/20 0.43
▸ DYRK1A Q13627 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24553788 1.00 MAPK14 (0.56) MAPK14CSNK1DWNT3AGSK3BMEN1
SCHEMBL24554160 0.92 MAPK14 (0.50) MAPK14CSNK1DWNT3AGSK3BNR3C2
SCHEMBL29683094 0.91 NR3C2 (0.46) MAPK14CSNK1DGSK3BNR3C2
SCHEMBL29683070 0.91 MAPK14 (0.49) MAPK14CSNK1DGSK3BNR3C2
SCHEMBL24554207 0.91 NR3C2 (0.46) MAPK14CSNK1DGSK3BNR3C2
SCHEMBL24554162 0.91 MAPK14 (0.49) MAPK14CSNK1DGSK3BNR3C2
SCHEMBL29683307 0.90 MAPK14 (0.55) MAPK14CSNK1DWNT3AGSK3B
SCHEMBL24553851 0.90 MAPK14 (0.55) MAPK14CSNK1DWNT3AGSK3B
SCHEMBL24554288 0.89 RIPK3 (0.46) MAPK14CSNK1DGSK3BNR3C2
SCHEMBL24553771 0.89 MAPK14 (0.46) MAPK14CSNK1DGSK3BNR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250276972-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) 2025-09-04 — — US disclosed
WO-2022127756-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS Gritscience Biopharmaceuticals Co., Ltd. (CN) 2022-06-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276972-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS PACSIN2, CSNK1A1, CSNK1G3 MAPK14 219/4885CSNK1D 12/4885WNT3A 1828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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