Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 18/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29683094 | 1.00 | NR3C2 (0.46) | NR3C2MAPK14CSNK1DMAPK13MAPK12 | |
| SCHEMBL29683070 | 0.93 | MAPK14 (0.49) | NR3C2MAPK14CSNK1DMAPK13MAPK12 | |
| SCHEMBL24554162 | 0.93 | MAPK14 (0.49) | NR3C2MAPK14CSNK1DMAPK13MAPK12 | |
| SCHEMBL29683167 | 0.91 | MAPK14 (0.56) | NR3C2MAPK14CSNK1DGSK3B | |
| SCHEMBL24554288 | 0.91 | RIPK3 (0.46) | NR3C2MAPK14CSNK1DMAPK13MAPK12 | |
| SCHEMBL24553788 | 0.91 | MAPK14 (0.56) | NR3C2MAPK14CSNK1DGSK3B | |
| SCHEMBL24553781 | 0.90 | MAPK14 (0.46) | NR3C2MAPK14CSNK1DGSK3B | |
| SCHEMBL25223642 | 0.90 | NR3C2 (0.46) | NR3C2MAPK14CSNK1DMAPK13MAPK12 | |
| SCHEMBL24553697 | 0.90 | MAPK14 (0.53) | MAPK14CSNK1DMAPK13MAPK12KCNH2 | |
| SCHEMBL29682944 | 0.90 | MAPK14 (0.53) | MAPK14CSNK1DMAPK13MAPK12KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744926-A | Compounds as inhibitors of casein kinase | 北京原基华毅生物科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022127756-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2022-06-23 | — | — | WO | disclosed |