Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19456492 | 0.88 | MMP14 (0.56) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL20588507 | 0.87 | MMP14 (0.54) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL20588505 | 0.87 | MMP14 (0.54) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL2002779 | 0.86 | MMP14 (0.78) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL13401334 | 0.86 | MMP14 (0.78) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL31672216 | 0.86 | MMP14 (0.78) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL17766830 | 0.83 | MMP14 (0.56) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL16377653 | 0.83 | MMP14 (0.56) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL25712978 | 0.83 | MMP14 (0.61) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL18025268 | 0.82 | MAPT (0.49) | MMP14MAPTALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220195500-A1 | PROBES FOR DETECTING RNA AND METHODS OF USE THEREOF | VANDERBILT UNIVERSITY | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220195500-A1 | PROBES FOR DETECTING RNA AND METHODS OF USE THEREOF | RNGTT, NSUN3, NSUN2 | MMP14 1433/4885MAPT 4550/4885ALDH1A1 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.