Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24881978 | 0.92 | SMN1; SMN2 (0.60) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL24155763 | 0.92 | SMN1; SMN2 (0.58) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL21674168 | 0.92 | NPC1 (0.71) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL21674267 | 0.90 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL26536336 | 0.89 | SMN1; SMN2 (0.57) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL24155740 | 0.88 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL22023371 | 0.88 | SMN1; SMN2 (0.58) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL19846114 | 0.88 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL18646304 | 0.88 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL24881965 | 0.88 | SMN1; SMN2 (0.63) | NPC1RAB9AMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220209132-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | Changchun Hyperions Technology Co., Ltd. (CN) | 2022-06-30 | — | — | US | disclosed |
| EP-4019503-A2 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | Changchun Hyperions Technology Co., Ltd. (CN) | 2022-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220209132-A1 | HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | EML4, STOM, GJB2 | NPC1 3939/4885RAB9A 1754/4885MEN1 879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.