Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2455744 | 1.00 | FPR3 (0.33) | FPR3FPR2EPHX2ALDH1A1KDM4E | |
| SCHEMBL2452335 | 0.89 | ALDH1A1 (0.34) | EPHX2ALDH1A1 | |
| SCHEMBL2452337 | 0.89 | ALDH1A1 (0.34) | EPHX2ALDH1A1 | |
| SCHEMBL2452729 | 0.79 | — | — | |
| SCHEMBL2452733 | 0.79 | — | — | |
| SCHEMBL16538439 | 0.79 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL337263 | 0.76 | CYP3A4 (0.32) | EPHX2ALDH1A1 | |
| SCHEMBL28525796 | 0.76 | CYP3A4 (0.32) | — | |
| SCHEMBL28527648 | 0.76 | CYP3A4 (0.32) | — | |
| SCHEMBL337878 | 0.75 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366700-A1 | Pyrrolidine-thioxopyrimidinone/thiohydantoin organocatolysts | National and Kapodistrian Universty of Athens (GR) | 2011-09-21 | — | — | EP | disclosed |