SCHEMBL2455941

SCHEMBL2455941

CC(C)=CCC/C(C)=C/CCP(=O)(O)O

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FNTA P49354 3/20 0.64
FNTB P49356 2/20 0.64
BTN3A1 O00481 1/20 0.62
KMT2A Q03164 1/20 0.61
GGPS1 O95749 2/20 0.61
PGGT1B P53609 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2455947 1.00 FNTA (0.64) FNTAFNTBBTN3A1KMT2AGGPS1
SCHEMBL9061131 1.00 FNTA (0.64) FNTAFNTBBTN3A1KMT2AGGPS1
SCHEMBL9061139 1.00 FNTA (0.64) FNTAFNTBBTN3A1KMT2AGGPS1
SCHEMBL7921058 1.00 FNTA (0.64) FNTAFNTBBTN3A1KMT2AGGPS1
SCHEMBL7921064 1.00 FNTA (0.64) FNTAFNTBBTN3A1KMT2AGGPS1
Phosphonic Acid SCHEMBL5400267 0.93 FNTA (0.57) FNTAFNTBBTN3A1KMT2AGGPS1
SCHEMBL10452651 0.89 FNTA (0.60) FNTAFNTB
SCHEMBL9633830 0.89 FNTA (0.60) FNTAFNTB
SCHEMBL9633822 0.89 FNTA (0.60) FNTAFNTB
SCHEMBL10452653 0.89 FNTA (0.60) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8017596-B2 Phosphonates useful as modulators of T-γ-9-δ-2 activity INNATE PHARMA, S.A. (FR) 2011-09-13 US disclosed
US-8017596-B2 Phosphonates useful as modulators of T-γ-9-δ-2 activity INNATE PHARMA, S.A. (FR) 2011-09-13 US disclosed
US-20100204184-A1 Phosphonates useful as modulators of T-gamma-9-delta-2 activity LABORATOIRES MAYOLY SPINDLER (FR) 2010-08-12 US disclosed
US-20100204184-A1 Phosphonates useful as modulators of T-gamma-9-delta-2 activity LABORATOIRES MAYOLY SPINDLER (FR) 2010-08-12 US disclosed
US-20060241087-A1 Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity MONTERO JEAN-LOUIS 2006-10-26 US disclosed
EP-1453840-A1 PHOSPHONATES USEFUL AS MODULATORS OF T-GAMMA-9-DELTA-2 LYMPHOCYTE ACTIVITY Laboratoire Mayoly Spindler (FR) 2004-09-08 EP disclosed
WO-2003050128-A1 PHOSPHONATES USEFUL AS MODULATORS OF T $G(G)9$G(D)2 LYMPHOCYTE ACTIVITY LABORATOIRE MAYOLY SPINDLER (FR) 2003-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204184-A1 Phosphonates useful as modulators of T-gamma-9-delta-2 activity CD4, PRKCD, PRKCZ FNTA 902/4885FNTB 556/4885BTN3A1 417/4885
US-20060241087-A1 Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity CD4, GNG2, PLCG2 FNTA 885/4885FNTB 1357/4885BTN3A1 797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.