Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.41 |
| ▸ | RARG | P13631 | 5/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24559663 | 0.87 | RARB (0.36) | RARBRARGRARAGAANCOA3 | |
| SCHEMBL22644229 | 0.85 | RARA (0.39) | RARBRARGRARAGAANCOA3 | |
| SCHEMBL22644241 | 0.84 | KDM1A (0.36) | RARBRARGRARAGAANCOA3 | |
| SCHEMBL22635921 | 0.79 | RARA (0.35) | RARBRARGRARAGAANCOA3 | |
| SCHEMBL24559474 | 0.79 | RARA (0.35) | RARBRARGRARAGAANCOA3 | |
| SCHEMBL22644230 | 0.79 | RARA (0.35) | RARBRARGRARAGAANCOA3 | |
| SCHEMBL24559506 | 0.74 | S1PR5 (0.40) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL15046513 | 0.74 | RARA (0.43) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL22644213 | 0.74 | PPARG (0.33) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL29240603 | 0.74 | PPARG (0.33) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966871-B1 | DIAMONDOID COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-05-03 | — | — | EP | disclosed |
| US-20220209150-A1 | DIAMONDOID COMPOUNDS | MERCK PATENT GMBH (DE) | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220209150-A1 | DIAMONDOID COMPOUNDS | CCND2, ZYX, CCNB2 | RARB 1454/4885RARG 813/4885RARA 2289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.