Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.52 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 2/20 | 0.51 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24559495 | 0.87 | POLB (0.52) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL29327116 | 0.87 | POLB (0.78) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL23679761 | 0.87 | POLB (0.78) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL20325348 | 0.86 | POLB (0.64) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL22524067 | 0.86 | POLB (0.64) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL20434931 | 0.86 | POLB (0.64) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL20325346 | 0.86 | POLB (0.64) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL12714688 | 0.85 | POLB (0.67) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL24059912 | 0.84 | POLB (0.66) | POLBP2RY2P2RY4P2RY6NT5E | |
| SCHEMBL5709934 | 0.84 | POLB (0.66) | POLBP2RY2P2RY4P2RY6NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204973-A1 | Antisense Oligonucleotide for Targeting Progranulin | HOFFMANN LA ROCHE (US) | 2022-06-30 | — | — | US | disclosed |