SCHEMBL2456072

SCHEMBL2456072

C=CN1C(=O)CCC1c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM5 P08912 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
SRD5A1 P18405 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
RIPK1 Q13546 3/20 0.43
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP3A4 P08684 1/20 0.40
THRB P10828 1/20 0.40
TSHR P16473 1/20 0.40
THPO P40225 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
DDB1 Q16531 1/20 0.38
CRBN Q96SW2 1/20 0.38
SRD5A2 P31213 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18366270 0.74 CHRM2 (0.47) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL13225803 0.74 KDM4E (0.66) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL20646025 0.74 CHRM2 (0.47) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11708369 0.74 KDM4E (0.66) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL28413243 0.74 L3MBTL1 (0.49) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL3739324 0.73 HDAC6 (0.54) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL19411904 0.72 HDAC6 (0.41) DDB1CRBN
SCHEMBL19411905 0.72 HDAC6 (0.41) DDB1CRBN
SCHEMBL28898304 0.72 IDH1 (0.42) RIPK1
SCHEMBL25017953 0.70 CHRM2 (0.57) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761587-B1 PLASTISOLS BASED ON A METHYLMETHACRYLATE COPOLYMER EVONIK ROEHM GMBH (DE) 2010-01-20 EP claimed
US-6686321-B2 MIXTURE; LUBRICANT OIL ADDITIVE CASTROL LIMITED (GB) 2004-02-03 US claimed
EP-1104495-A4 SELECTIVE RETENTION OF FILLING COMPONENTS AND IMPROVED CONTROL OF SHEET PROPERTIES BY ENHANCING ADDITIVE PRETREATMENT NALCO CHEMICAL CO (US) 2002-07-24 EP claimed
EP-1104495-A1 SELECTIVE RETENTION OF FILLING COMPONENTS AND IMPROVED CONTROL OF SHEET PROPERTIES BY ENHANCING ADDITIVE PRETREATMENT NALCO CHEMICAL COMPANY (US) 2001-06-06 EP claimed
WO-2000049227-A1 SELECTIVE RETENTION OF FILLING COMPONENTS AND IMPROVED CONTROL OF SHEET PROPERTIES BY ENHANCING ADDITIVE PRETREATMENT NALCO CHEMICAL COMPANY (US) 2000-08-24 WO claimed
EP-0434362-B1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution TOMEI SANGYO KK (JP) 1995-03-22 EP claimed
EP-0433046-B1 Polymer-type polymerization initiator TOMEI SANGYO KK (JP) 1994-08-10 EP claimed
US-5206298-A GRAFT COPOLYMER, SOLUTION CONTAINING THE GRAFT COPOLYMER FOR TREATING CONTACT LENS, AND METHOD OF TREATING CONTACT LENS WITH THE SOLUTION AND MAKING HYDROPHILIC LENS SURFACE TOMEI SANGYO KABUSHIKI KAISHA (JP) 1993-04-27 US claimed
US-5134213-A N-Vinyllactam-Monoperoxyfumarate Terpolymer TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-07-28 US claimed
US-5082912-A For graft polymerization, surfactants TOMEI SANGYO KABUSHIKI KAISHA (JP) 1992-01-21 US claimed
EP-0434362-A1 Graft copolymer, solution containing the graft copolymer, and method of treating contact lens with the solution Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-26 EP claimed
EP-0433046-A2 Polymer-type polymerization initiator Tomei Sangyo Kabushiki Kaisha (JP) 1991-06-19 EP claimed
US-4772359-A POLY-N-VINYLAMIDE AS DRAINAGE AID BASF AKTIENGESELLSCHAFT (DE) 1988-09-20 US claimed
EP-0249891-A1 Process for producing paper and cardboard BASF Aktiengesellschaft (DE) 1987-12-23 EP claimed
US-4170561-A Lubricating compositions with lactam or thiolactam-containing copolymers ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERES (E.R.A.P.) (FR) 1979-10-09 US claimed
US-20220024102-A1 Acrylic foils with improved UV-protection properties RÖHM GMBH (DE) 2022-01-27 US disclosed
EP-3659798-B1 ACRYLIC FOILS WITH IMPROVED UV-PROTECTION PROPERTIES ROEHM GMBH (DE) 2021-09-08 EP disclosed
US-4170561-A Lubricating compositions with lactam or thiolactam-containing copolymers ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERES (E.R.A.P.) (FR) 1979-10-09 US disclosed
US-4092255-A ETHYLENE-MONOOLEFIN-NON-CONJUGATED DIENE TERPOLYMER WITH A VINYL IMIDAZOL(IN)E OR ALKENYL CARBAZOLE MONOMER ENTREPRISE DE RECHERCHES ET D'ACTIVITES PETROLIERES (E.R.A.P.) (FR) 1978-05-30 US disclosed
US-3939129-A Process for the preparation of random copolymers of mono-olefins or of mono-olefins and unconjugated dienes with lactams with substitution on the nitrogen atom by an unsaturated radical SOCIETE NATIONALE DES PETROLES D'AQUITAINE (FR) 1976-02-17 US disclosed