Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473284 | 0.81 | S1PR1 (0.40) | S1PR1S1PR3MAPTTP53 | |
| SCHEMBL2472405 | 0.81 | RARA (0.40) | S1PR1S1PR3MAPT | |
| SCHEMBL2456203 | 0.79 | S1PR1 (0.44) | S1PR1S1PR3 | |
| SCHEMBL2470344 | 0.78 | CA9 (0.48) | S1PR1 | |
| SCHEMBL2476438 | 0.76 | MAPK1 (0.39) | S1PR1S1PR3MAPT | |
| SCHEMBL2473364 | 0.76 | MAPT (0.42) | S1PR1MAPTTP53 | |
| SCHEMBL2472532 | 0.76 | CDK4 (0.36) | S1PR1MAPTALOX5APPIK3CAMTOR | |
| SCHEMBL2474719 | 0.75 | DGAT1 (0.39) | S1PR1S1PR3MAPTDGAT1BCL2L1 | |
| SCHEMBL2467513 | 0.74 | S1PR1 (0.38) | S1PR1S1PR3MAPT | |
| SCHEMBL2470317 | 0.74 | BCL2L1 (0.37) | S1PR1S1PR3MAPTDGAT1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113578-A1 | NEW OXADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-09-22 | — | — | WO | claimed |
| EP-2366702-A1 | New oxadiazole derivatives | Almirall, S.A. (ES) | 2011-09-21 | — | — | EP | claimed |
| WO-2011113578-A1 | NEW OXADIAZOLE DERIVATIVES | ALMIRALL, S.A. (ES) | 2011-09-22 | — | — | WO | disclosed |
| EP-2366702-A1 | New oxadiazole derivatives | Almirall, S.A. (ES) | 2011-09-21 | — | — | EP | disclosed |
| EP-2366702-A1 | New oxadiazole derivatives | Almirall, S.A. (ES) | 2011-09-21 | — | — | EP | disclosed |