Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 19/20 | 0.52 |
| ▸ | THRB | P10828 | 19/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565182 | 0.94 | THRA (0.59) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL27166007 | 0.94 | THRA (0.48) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL23260061 | 0.89 | THRA (0.67) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL24565092 | 0.83 | THRA (0.54) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL28656735 | 0.82 | THRB (0.55) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL31405749 | 0.81 | THRA (0.52) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL25673785 | 0.80 | THRA (0.79) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL24565094 | 0.78 | THRA (0.62) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL23571218 | 0.77 | THRA (0.43) | THRATHRBCYP2C9CYP2C8 | |
| SCHEMBL29497536 | 0.76 | THRA (0.70) | THRATHRBCYP2C9CYP2C8UGT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019510-A1 | HALOGEN-SUBSTITUTED PHENYLATE COMPOUND AND APPLICATIONS THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-06-29 | — | — | EP | disclosed |