Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 12/20 | 0.47 |
| ▸ | INSR | P06213 | 8/20 | 0.47 |
| ▸ | IGF1R | P08069 | 7/20 | 0.47 |
| ▸ | EGFR | P00533 | 7/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24565268 | 0.88 | ALK (0.47) | ALKINSRIGF1REGFRMAP4K1 | |
| SCHEMBL24565479 | 0.81 | ROS1 (0.59) | ALKEGFRMET | |
| SCHEMBL24565201 | 0.79 | ROS1 (0.59) | ALKEGFRMET | |
| SCHEMBL24565166 | 0.76 | EGFR (0.55) | ALKEGFRMET | |
| SCHEMBL24565337 | 0.76 | EGFR (0.51) | ALKINSRIGF1REGFR | |
| SCHEMBL24565262 | 0.75 | MAP4K1 (0.57) | IGF1RMAP4K1 | |
| SCHEMBL24565257 | 0.74 | MAP4K1 (0.52) | ALKIGF1REGFRMAP4K1 | |
| SCHEMBL24565260 | 0.74 | EGFR (0.58) | ALKINSREGFRMET | |
| SCHEMBL24565264 | 0.72 | EGFR (0.56) | ALKINSREGFRMET | |
| SCHEMBL22459946 | 0.72 | EGFR (0.55) | ALKINSRIGF1REGFRMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022139386-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 주식회사 비투에스바이오 | 2022-06-30 | — | — | WO | disclosed |