Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107596 | 1.00 | MAPT (0.52) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL9691586 | 1.00 | MAPT (0.52) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL9692534 | 0.92 | MAPT (0.50) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL8644758 | 0.92 | MAPT (0.50) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL11012592 | 0.91 | ITGB1 (0.50) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10418465 | 0.91 | ITGB1 (0.50) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10418464 | 0.91 | ITGB1 (0.50) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10418049 | 0.90 | ITGB1 (0.49) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL9691582 | 0.90 | ITGB1 (0.49) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10418050 | 0.90 | ITGB1 (0.49) | MAPTMEN1ALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445476-B2 | Carbacephem β-lactam antibiotics | ACHAOGEN, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20110224186-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010123997-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-10-28 | — | — | WO | disclosed |
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-10-21 | — | — | US | disclosed |
| EP-2205600-A1 | CARBACEPHEM ß -LACTAM ANTIBIOTICS | Achaogen, Inc. (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2010030810-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010030811-A2 | CARBACEPHEM β-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2009055696-A1 | CARBACEPHEM β-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2009-04-30 | — | — | WO | disclosed |
| US-6927290-B2 | Production of mixed acid anhydride and amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-08-09 | — | — | US | disclosed |
| US-20040210059-A1 | Production of mixed acid anhydride and amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-10-21 | — | — | US | disclosed |
| EP-0095778-A1 | 2-Oxo-1-azetidinesulfonic acid derivatives, process for production thereof, and use thereof | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1983-12-07 | — | — | EP | disclosed |
| US-4411898-A | CEPHALOSPORIN ANTIBACTERIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-25 | — | — | US | disclosed |
| US-4400379-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-08-23 | — | — | US | disclosed |
| US-4399133-A | ADMINISTERING, INFECTIONS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-08-16 | — | — | US | disclosed |
| US-4393059-A | BACTERICIDAL CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-07-12 | — | — | US | disclosed |
| US-4367228-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-04 | — | — | US | disclosed |
| US-4331664-A | BACTERIOSTATS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4294960-A | 7-[2-(2-Aminothiazol-4-yl)-2-cyclopentyloxyiminoacetamido]-3-cephem-4-carboxylic acid (synisomer) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-10-13 | — | — | US | disclosed |
| US-4288436-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-08 | — | — | US | disclosed |
| US-4196205-A | ANTIBIOTICS, BACTERICIDES | ROUSSEL UCLAF (FR) | 1980-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224186-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | MGAM, MGAM2, B2M | MAPT 3937/4885MEN1 2327/4885ALDH1A1 2455/4885 |
| US-20100267686-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | MGAM, MGAM2, B2M | MAPT 3888/4885MEN1 2194/4885ALDH1A1 2468/4885 |
| US-20040210059-A1 | Production of mixed acid anhydride and amide compound | CA2, CA1, CA3 | MAPT 4620/4885MEN1 2071/4885ALDH1A1 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.