SCHEMBL2456543

SCHEMBL2456543

CC(C)COC(=O)CC(C(=O)OCC(C)C)C(C)(C)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.36
PRKCA P17252 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2457697 0.85 PRKCA (0.39) TSHRPRKCAALDH1A1TDP1L3MBTL1
SCHEMBL974546 0.80 GAA (0.40) TSHRALDH1A1TDP1L3MBTL1
SCHEMBL2453413 0.79
SCHEMBL2456542 0.78 TSHR (0.34) TSHRPRKCAALDH1A1TDP1L3MBTL1
SCHEMBL2859945 0.74 RAB9A (0.35) TSHRRAB9A
SCHEMBL128660 0.74 TSHR (0.48) TSHRPRKCAALDH1A1TDP1L3MBTL1
SCHEMBL28755335 0.73 TDP1 (0.36) TSHRPRKCATDP1
SCHEMBL27017168 0.73 TSHR (0.41) TSHRPRKCAALDH1A1TDP1L3MBTL1
SCHEMBL2455247 0.73 TSHR (0.37) TSHRPRKCAALDH1A1TDP1L3MBTL1
SCHEMBL15491409 0.72 TSHR (0.43) TSHRPRKCAALDH1A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209125-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2024-06-27 US disclosed
EP-3559113-B1 MASTERBATCH COMPOSITION BASELL POLIOLEFINE ITALIA SRL (IT) 2024-06-12 EP disclosed
EP-4323415-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2024-02-21 EP disclosed
EP-3765566-B1 POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE BASELL POLIOLEFINE ITALIA SRL (IT) 2023-12-06 EP disclosed
US-11807744-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2023-11-07 US disclosed
CN-116997578-A Prepolymerized catalyst component for olefin polymerization 巴塞尔聚烯烃意大利有限公司 2023-11-03 CN disclosed
WO-2022218869-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-10-20 WO disclosed
US-11339280-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-05-24 US disclosed
US-11319431-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-05-03 US disclosed
US-11306198-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-04-19 US disclosed
US-7005487-B2 Catalyst system for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2006-02-28 US disclosed
EP-1539838-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.P.A. (IT) 2005-06-15 EP disclosed
EP-1525231-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.P.A. (IT) 2005-04-27 EP disclosed
US-20050032633-A1 Propylene polymers BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-02-10 US disclosed
US-20050014631-A1 Catalyst system for the polymerization of olefins BASELL POLYOLEFINE ITALIA S.P.A. (IT) 2005-01-20 US disclosed
US-6818583-B1 HIGH YIELDS AND HIGH ISOTACTIC INDEX; COMPRISING MG, TI, HALOGEN AND A SUCCINATE ELECTRON DONOR BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-16 US disclosed
WO-2004024785-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-03-25 WO disclosed
WO-2004005359-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-01-15 WO disclosed
EP-1088009-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-04-04 EP disclosed
WO-2000063261-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-10-26 WO disclosed