Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ERN1 | O75460 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL27920670 | 0.82 | CYP3A4 (0.53) | KMT2AMAPTHSP90AA1MEN1LMNA | |
| SCHEMBL5150835 | 0.79 | ERN1 (0.50) | KMT2AMAPTHSP90AA1MEN1LMNA | |
| SCHEMBL29956480 | 0.78 | KDM4E (0.58) | KMT2AMAPTHSP90AA1MEN1LMNA | |
| SCHEMBL1071836 | 0.78 | KDM4E (0.58) | KMT2AMAPTHSP90AA1MEN1LMNA | |
| SCHEMBL13749211 | 0.78 | ERN1 (0.65) | KMT2AMAPTHSP90AA1MEN1LMNA | |
| SCHEMBL1085388 | 0.78 | MAPT (1.00) | KMT2AMAPTHSP90AA1MEN1LMNA | |
| SCHEMBL29661896 | 0.78 | MAPT (1.00) | KMT2AMAPTHSP90AA1MEN1LMNA | |
| SCHEMBL3409403 | 0.77 | KDM4E (0.56) | KMT2AMAPTHSP90AA1MEN1LMNA | |
| SCHEMBL1161054 | 0.77 | KDM4E (0.56) | KMT2AMAPTHSP90AA1MEN1LMNA | |
| SCHEMBL29951440 | 0.77 | ERN1 (0.64) | KMT2AMAPTHSP90AA1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044284-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-11-13 | — | — | EP | disclosed |
| US-9831448-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-9831448-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-11-28 | — | — | US | disclosed |
| US-20160233443-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20160233443-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| EP-1341403-B1 | LUMINESCENT ELEMENT MATERIAL AND LUMINESCENT ELEMENT COMPRISING THE SAME | TORAY INDUSTRIES (JP) | 2016-05-11 | — | — | EP | disclosed |
| WO-2015036074-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-03-19 | — | — | WO | disclosed |
| EP-2365735-B1 | Luminescent element material and luminescent element comprising the same | TORAY INDUSTRIES (JP) | 2013-08-28 | — | — | EP | disclosed |
| EP-2365735-A2 | Luminescent element material and luminescent element comprising the same | TORAY INDUSTRIES INC. (JP) | 2011-09-14 | — | — | EP | disclosed |
| US-7318966-B2 | Luminescent element material and luminescent element comprising the same | TORAY INDUSTRIES, INC. (JP) | 2008-01-15 | — | — | US | disclosed |
| US-20030168970-A1 | Luminescent element material and luminescent element comprising the same | TORAY INDUSTRIES, INC. (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1341403-A1 | LUMINESCENT ELEMENT MATERIAL AND LUMINESCENT ELEMENT COMPRISING THE SAME | Toray Industries, Inc. (JP) | 2003-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160233443-A1 | Metal Complexes | AP1M1, SOD1, AP3M1 | KMT2A 2648/4885MAPT 1084/4885HSP90AA1 4306/4885 |
| US-20030168970-A1 | Luminescent element material and luminescent element comprising the same | SAAL1, EBPL, CSNK1A1L | KMT2A 3458/4885MAPT 4865/4885HSP90AA1 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.