Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13713266 | 0.82 | GNAI3 (0.47) | KDM1AGNAI3GNAO1GNAI1NCF1 | |
| SCHEMBL10221907 | 0.80 | MGAT2 (0.37) | KDM1AHPGDSGPR119 | |
| SCHEMBL2740581 | 0.75 | HTT (0.40) | — | |
| SCHEMBL13713265 | 0.74 | ALDH1A1 (0.42) | KDM1ANCF1 | |
| SCHEMBL25025562 | 0.74 | KDM1A (0.33) | KDM1AHPGDSGPR119 | |
| SCHEMBL19223404 | 0.73 | MGAT2 (0.33) | KDM1A | |
| SCHEMBL19223408 | 0.73 | MGAT2 (0.33) | KDM1A | |
| SCHEMBL18133863 | 0.73 | MGAT2 (0.33) | KDM1A | |
| SCHEMBL25024519 | 0.73 | KDM1A (0.33) | KDM1AHPGDSGPR119 | |
| SCHEMBL25025564 | 0.73 | KDM1A (0.33) | KDM1AHPGDSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781563-B1 | HPK1 INHIBITORS, PREPARATION METHOD AND APPLICATION THEREOF | ZHUHAI YUFAN BIOTECHNOLOGIES CO LTD (CN) | 2022-06-29 | — | — | EP | disclosed |