Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17700093 | 1.00 | FDPS (0.50) | FDPSMEN1MAPK10GFERKMT2A | |
| SCHEMBL85479 | 0.83 | FDPS (0.53) | FDPSMEN1MAPK10GFERKMT2A | |
| Ammonia Solution, Strong SCHEMBL4034014 | 0.81 | FDPS (0.52) | FDPSMEN1MAPK10GFERKMT2A | |
| SCHEMBL27442083 | 0.79 | FDPS (0.50) | FDPSMEN1MAPK10GFERKMT2A | |
| SCHEMBL3644137 | 0.79 | FDPS (0.55) | FDPSMEN1MAPK10GFERKMT2A | |
| SCHEMBL27542187 | 0.79 | FDPS (0.50) | FDPSMEN1MAPK10GFERKMT2A | |
| SCHEMBL16126083 | 0.79 | FDPS (0.50) | FDPSMEN1MAPK10GFERKMT2A | |
| SCHEMBL25083172 | 0.79 | FDPS (0.50) | FDPSMEN1MAPK10GFERKMT2A | |
| SCHEMBL9641327 | 0.79 | FDPS (0.50) | FDPSMEN1MAPK10GFERKMT2A | |
| SCHEMBL20025127 | 0.79 | FDPS (0.50) | FDPSMEN1MAPK10GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |