SCHEMBL85479

SCHEMBL85479

CC(C)Nc1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.53
MEN1 O00255 1/20 0.50
MAPK10 P53779 1/20 0.50
GFER P55789 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4E B2RXH2 2/20 0.49
HTT P42858 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
POLB P06746 1/20 0.47
NPC1 O15118 1/20 0.47
PKM P14618 1/20 0.47
RAB9A P51151 1/20 0.47
CYP1A2 P05177 1/20 0.46
CXCR4 P61073 1/20 0.45
LMNA P02545 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL4034014 0.98 FDPS (0.52) FDPSMEN1MAPK10GFERKMT2A
SCHEMBL28673545 0.92 CYP2C19 (0.47) FDPSMEN1MAPK10GFERKMT2A
SCHEMBL19581187 0.86 KDM4E (0.43) FDPSMEN1MAPK10GFERKMT2A
SCHEMBL19581183 0.86 KDM4E (0.43) FDPSMEN1MAPK10GFERKMT2A
Dichloroacetic Acid SCHEMBL10510997 0.84 POLB (0.51) FDPSMEN1KMT2AKDM4EL3MBTL1
SCHEMBL24567486 0.83 FDPS (0.50) FDPSMEN1MAPK10GFERKMT2A
SCHEMBL9641327 0.83 FDPS (0.50) FDPSMEN1MAPK10GFERKMT2A
SCHEMBL3644137 0.83 FDPS (0.55) FDPSMEN1MAPK10GFERKMT2A
SCHEMBL25083172 0.83 FDPS (0.50) FDPSMEN1MAPK10GFERKMT2A
SCHEMBL16126083 0.83 FDPS (0.50) FDPSMEN1MAPK10GFERKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111491918-B Aryl and heteroaryl substituted indole compounds 百时美施贵宝公司 2023-10-24 CN claimed
US-20200035418-A1 PASSIVATION OF DEFECTS IN PEROVSKITE MATERIALS FOR IMPROVED SOLAR CELL EFFICIENCY AND STABILITY NUTECH VENTURES 2020-01-30 US claimed
WO-2018152494-A1 PASSIVATION OF DEFECTS IN PEROVSKITE MATERIALS FOR IMPROVED SOLAR CELL EFFICIENCY AND STABILITY NUTECH VENTURES (US) 2018-08-23 WO claimed
CN-108026099-A The aminopyridine compounds substituted through heteroaryl 百时美施贵宝公司 2018-05-11 CN claimed
CN-119684291-A Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy 艾科思莱德制药公司 2025-03-25 CN disclosed
US-20240239828-A1 MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2024-07-18 US disclosed
US-RE50030-E1 Methods to treat lymphoplasmacytic lymphoma DANA-FARBER CANCER INSTITUTE, INC. (US) 2024-07-02 US disclosed
CN-114560886-B Precursor aminopyridyl Ni (II) compound for information storage material 许昌学院 2024-03-19 CN disclosed
WO-2024054469-A1 ISOQUINOLONES AS PI3K INHIBITORS ONKURE, INC. (US) 2024-03-14 WO disclosed
US-11919858-B2 Aminonapthoquinone compounds and pharmaceutical composition for blocking ubiquitination-proteasome system in diseases CALGENT BIOTECHNOLOGY CO., LTD. (TW) 2024-03-05 US disclosed
US-20240072809-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2024-02-29 US disclosed
US-20240072809-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2024-02-29 US disclosed
US-6194490-B1 MIXTURES OF EPOXIDES WITH ANHYDRIDES AND CURING VANTICO, INC. 2001-02-27 US disclosed
CN-1277198-A New bicyclo aminopyrazineone compound, its producing process and medical composition containing them ADIR (FR) 2000-12-20 CN disclosed
EP-1058702-A1 CURABLE COMPOSITION COMPRISING EPOXIDISED NATURAL OILS Vantico AG (CH) 2000-12-13 EP disclosed
EP-0977743-A1 PROTEASE INHIBITORS Smithkline Beecham (US) 2000-02-09 EP disclosed
EP-0949230-A1 PROCESSES FOR PRODUCING ALKENYL-SUBSTITUTED AROMATIC HYDROCARBONS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1999-10-13 EP disclosed
WO-1999043729-A1 CURABLE COMPOSITION COMPRISING EPOXIDISED NATURAL OILS VANTICO AG (CH) 1999-09-02 WO disclosed
WO-1998049152-A1 PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1998-11-05 WO disclosed
EP-0305184-A1 Pyrimidines or their pharmaceutically acceptable salts thereof MITSUI PHARMACEUTICALS, INC. (JP) 1989-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239828-A1 MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS M6PR, ASGR1, IGF2R FDPS 2194/4885MEN1 641/4885MAPK10 1613/4885
US-11919858-B2 Aminonapthoquinone compounds and pharmaceutical composition for blocking ubiquitination-proteasome system in diseases UBQLN1, PSMB1, UBQLN2 FDPS 2360/4885MEN1 2805/4885MAPK10 2550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.