Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 11/20 | 0.39 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.39 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456743 | 0.83 | PRKCI (0.42) | CHRM4GRM5ATR | |
| SCHEMBL2458764 | 0.77 | HDAC1 (0.48) | GRM5KDM4EALDH1A1 | |
| SCHEMBL2459809 | 0.77 | RAB9A (0.40) | CHRM4ADORA2AALDH1A1 | |
| SCHEMBL2456197 | 0.74 | PRKCI (0.45) | CHRM4KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL27607866 | 0.73 | KMT2A (0.43) | GRM5KDM4E | |
| SCHEMBL2454980 | 0.73 | EGFR (0.42) | CHRM4ADORA2A | |
| SCHEMBL2454948 | 0.72 | CNR1 (0.48) | CHRM4ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL27626866 | 0.70 | PRKCI (0.42) | CHRM4KDM4EALDH1A1 | |
| SCHEMBL2456714 | 0.70 | GPR183 (0.46) | ADORA2A | |
| SCHEMBL2454974 | 0.68 | NPC1 (0.43) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534277-B1 | ACYLATED, HETEROARYL-CONDENSED CYCLOALKENYLAMINES AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-14 | — | — | EP | disclosed |
| EP-1534277-B1 | ACYLATED, HETEROARYL-CONDENSED CYCLOALKENYLAMINES AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-14 | — | — | EP | disclosed |