Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 7/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 5/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456751 | 0.83 | CHRM4 (0.39) | ATRGRM5CHRM4 | |
| SCHEMBL2456197 | 0.82 | PRKCI (0.45) | PRKCICHRM4 | |
| SCHEMBL23770088 | 0.82 | ATR (0.54) | PRKCIATRGRM5PIM1PIM3 | |
| Trifluoroacetic Acid SCHEMBL27626866 | 0.79 | PRKCI (0.42) | PRKCICHRM4 | |
| SCHEMBL3391271 | 0.77 | MTNR1A (0.55) | PRKCIATRGRM5PIM1PIM3 | |
| SCHEMBL3392202 | 0.77 | MTNR1A (0.55) | PRKCIATRGRM5PIM1PIM3 | |
| SCHEMBL23770330 | 0.72 | ACVR2A (0.54) | PRKCIATRPIM1PIM3PIM2 | |
| SCHEMBL2458764 | 0.71 | HDAC1 (0.48) | GRM5 | |
| SCHEMBL2459809 | 0.71 | RAB9A (0.40) | CHRM4 | |
| SCHEMBL21490091 | 0.71 | SMYD3 (0.51) | PRKCIATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534277-B1 | ACYLATED, HETEROARYL-CONDENSED CYCLOALKENYLAMINES AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-14 | — | — | EP | disclosed |
| EP-1534277-B1 | ACYLATED, HETEROARYL-CONDENSED CYCLOALKENYLAMINES AND THEIR USE AS PHARMACEUTICALS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-14 | — | — | EP | disclosed |