Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24567746 | 0.88 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL8483449 | 0.83 | L3MBTL1 (0.48) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL22202009 | 0.82 | L3MBTL1 (0.54) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL8483453 | 0.81 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL8488421 | 0.81 | L3MBTL1 (0.50) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL10082173 | 0.81 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL14300014 | 0.81 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL24503889 | 0.79 | MEN1 (0.48) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL22333372 | 0.79 | MEN1 (0.48) | L3MBTL1MEN1KMT2ATDP1ATM | |
| SCHEMBL8488426 | 0.79 | MEN1 (0.48) | L3MBTL1MEN1KMT2ATDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |