Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24503889 | 1.00 | MEN1 (0.48) | MEN1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL12446354 | 1.00 | MEN1 (0.48) | MEN1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL10082173 | 0.98 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL14300014 | 0.98 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL8488655 | 0.86 | MEN1 (0.46) | MEN1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL8488653 | 0.84 | L3MBTL1 (0.44) | MEN1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL8485259 | 0.83 | ATM (0.46) | MEN1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL19956481 | 0.82 | HTR1A (0.48) | L3MBTL1TDP1POLBNPSR1ALDH1A1 | |
| SCHEMBL21651963 | 0.82 | L3MBTL1 (0.48) | MEN1KMT2AL3MBTL1TDP1POLB | |
| SCHEMBL10936610 | 0.82 | PKM (0.47) | MEN1KMT2AL3MBTL1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526198-B1 | 3-SULFONYL-5-AMINOPYRIDINE-2,4-DIOL APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2020-08-12 | — | — | EP | disclosed |