Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20342450 | 0.75 | LMNA (0.47) | P2RX7LMNAMEN1KMT2AHDAC1 | |
| SCHEMBL12352043 | 0.75 | LMNA (0.47) | P2RX7LMNAMEN1KMT2AHDAC1 | |
| SCHEMBL13003596 | 0.73 | KMT2A (0.41) | P2RX7LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24501868 | 0.73 | KMT2A (0.41) | P2RX7LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6745604 | 0.73 | KMT2A (0.41) | P2RX7LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17154813 | 0.73 | LMNA (0.40) | P2RX7LMNAMEN1KMT2AHDAC1 | |
| SCHEMBL31201731 | 0.73 | LMNA (0.40) | P2RX7LMNAMEN1KMT2AHDAC1 | |
| SCHEMBL961068 | 0.73 | LMNA (0.40) | P2RX7LMNAMEN1KMT2AHDAC1 | |
| SCHEMBL30467058 | 0.73 | LMNA (0.40) | P2RX7LMNAMEN1KMT2AHDAC1 | |
| SCHEMBL17154815 | 0.73 | LMNA (0.40) | P2RX7LMNAMEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |