Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24568817 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDGAASTAT3 | |
| SCHEMBL24568810 | 0.84 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDGAASTAT3 | |
| SCHEMBL24568818 | 0.83 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDGAASTAT3 | |
| SCHEMBL24568815 | 0.82 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDGAASTAT3 | |
| SCHEMBL17179261 | 0.80 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDGAASTAT3 | |
| SCHEMBL24568814 | 0.80 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDGAASTAT3 | |
| SCHEMBL24568822 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1HPGDGAASTAT3 | |
| SCHEMBL8878501 | 0.78 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDGAASTAT3 | |
| SCHEMBL570984 | 0.75 | TLR8 (0.54) | KDM4EALDH1A1HPGDGAASTAT3 | |
| Trimethylammonium SCHEMBL27933253 | 0.74 | KDM4E (0.60) | KDM4EALDH1A1HPGDGAASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492340-B2 | Heteroaromatic electrophiles and methods of using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2022-11-08 | — | — | US | disclosed |
| US-20220204472-A1 | HETEROAROMATIC ELECTROPHILES AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492340-B2 | Heteroaromatic electrophiles and methods of using thereof | ACHE, BCHE, CHAT | KDM4E 3120/4885ALDH1A1 1025/4885HPGD 850/4885 |
| US-20220204472-A1 | HETEROAROMATIC ELECTROPHILES AND METHODS OF USING THEREOF | ACHE, BCHE, CHAT | KDM4E 3120/4885ALDH1A1 1025/4885HPGD 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.