Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24570929 | 0.80 | SRD5A1 (0.42) | SRD5A1CCR5LMNASMN1; SMN2OPRM1 | |
| SCHEMBL24570919 | 0.79 | SRD5A1 (0.44) | SRD5A1CCR5LMNAOPRM1OPRD1 | |
| SCHEMBL31158034 | 0.79 | SRD5A1 (0.44) | SRD5A1CCR5LMNAOPRM1OPRD1 | |
| SCHEMBL2571011 | 0.78 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2571280 | 0.78 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL2572769 | 0.78 | SRD5A1 (0.48) | SRD5A1CCR5OPRM1OPRD1OPRK1 | |
| SCHEMBL3866433 | 0.77 | CHRNA7 (0.46) | SRD5A1OPRM1OPRD1OPRK1 | |
| SCHEMBL22494227 | 0.77 | SRD5A1 (0.41) | SRD5A1OPRM1OPRD1OPRK1 | |
| SCHEMBL31151861 | 0.77 | SRD5A1 (0.41) | SRD5A1OPRM1OPRD1OPRK1 | |
| Ammonia Solution, Strong SCHEMBL9985508 | 0.76 | SRD5A1 (0.46) | SRD5A1CCR5OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118745144-A | Novel EZH2 inhibitor compound, and preparation method and application thereof | 辽宁大学 | 2024-10-08 | — | — | CN | disclosed |