Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469785 | 0.85 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1NR1D1HDAC3HDAC1 | |
| SCHEMBL16334088 | 0.85 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1NR1D1HDAC3HDAC1 | |
| SCHEMBL475682 | 0.82 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL12348353 | 0.80 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL11374230 | 0.79 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL16100071 | 0.79 | MEN1 (0.34) | ALDH1A1L3MBTL1LMNASTING1 | |
| SCHEMBL17521944 | 0.79 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1STING1 | |
| SCHEMBL4565384 | 0.79 | MEN1 (0.34) | ALDH1A1L3MBTL1LMNASTING1 | |
| SCHEMBL6712289 | 0.78 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL14754893 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204510-A1 | 2,3-DIHYDRO-1H-PYRROLIZINE-7-FORMAMIDE DERIVATIVE AND APPLICATION THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204510-A1 | 2,3-DIHYDRO-1H-PYRROLIZINE-7-FORMAMIDE DERIVATIVE AND APPLICATION THEREOF | DPYD, EIF2AK2, INF2 | ALDH1A1 2381/4885L3MBTL1 4828/4885NR1D1 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.