Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100071 | 1.00 | MEN1 (0.34) | MEN1KMT2ALMNABLMHBB | |
| SCHEMBL469785 | 0.93 | ALDH1A1 (0.34) | ALDH1A1STING1L3MBTL1 | |
| SCHEMBL17521944 | 0.87 | ALDH1A1 (0.31) | ALDH1A1STING1L3MBTL1 | |
| SCHEMBL12348353 | 0.85 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1 | |
| SCHEMBL14754893 | 0.84 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL6712289 | 0.82 | ALDH1A1 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL328634 | 0.82 | LMNA (0.48) | MEN1KMT2ALMNABLMHBB | |
| SCHEMBL12250920 | 0.81 | — | — | |
| SCHEMBL15000849 | 0.79 | HDAC3 (0.31) | — | |
| SCHEMBL24570975 | 0.79 | ALDH1A1 (0.46) | LMNAALDH1A1STING1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637705-A1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | King's College London (GB) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012063028-A1 | CONJUGATES AND THEIR USES IN MOLECULAR IMAGING | KING'S COLLEGE LONDON (GB) | 2012-05-18 | — | — | WO | disclosed |