⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760719 | 0.96 | NR1H2 (0.34) | — | |
| SCHEMBL25365911 | 0.96 | NR1H2 (0.34) | — | |
| Ammonia Solution, Strong SCHEMBL6823706 | 0.87 | TSHR (0.32) | — | |
| Dimethylamine SCHEMBL29203962 | 0.84 | ACHE (0.32) | — | |
| SCHEMBL14811593 | 0.83 | — | — | |
| SCHEMBL27603876 | 0.82 | CCNB2 (0.31) | — | |
| SCHEMBL31557612 | 0.80 | TSHR (0.38) | — | |
| SCHEMBL31557611 | 0.80 | TSHR (0.38) | — | |
| SCHEMBL24524284 | 0.80 | CYP3A4 (0.41) | — | |
| SCHEMBL27608982 | 0.76 | NR1H2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200332043-A1 | A QUADRIPOLYMER BASED ON HOST-GUEST INTERACTION AND PREPARATION PROCESS THEREOF | SOUTHWEST PETROLEUM UNIVERSITY (CN) | 2020-10-22 | — | — | US | claimed |
| CN-110392940-B | Solar cell and method for manufacturing same | 积水化学工业株式会社 | 2023-04-28 | — | — | CN | disclosed |
| CN-111841515-B | Ionic liquid bridged hybrid silicon oxide as water-rich chromatographic stationary phase and preparation method and application thereof | 镇江海关综合技术中心 | 2023-03-28 | — | — | CN | disclosed |
| CN-111841515-A | Ionic liquid bridged hybrid silicon oxide as water-rich chromatographic stationary phase and preparation method and application thereof | 镇江海关综合技术中心 | 2020-10-30 | — | — | CN | disclosed |
| US-20200199485-A1 | GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS | EXXONMOBIL RES & ENG CO (US) | 2020-06-25 | — | — | US | disclosed |
| WO-2018188990-A1 | BIOTIN-CONJUGATED N-ACETYL GLYCOL SPLIT HEPARIN | LEADIANT BIOSCIENCES SA IN LIQUIDAZIONE (CH) | 2018-10-18 | — | — | WO | disclosed |
| EP-3388419-A1 | GLI1 INHIBITORS AND USES THEREOF | Leadiant Biosciences SA (CH) | 2018-10-17 | — | — | EP | disclosed |
| EP-3388439-A1 | BIOTIN-CONJUGATED N-ACETYL GLYCOL SPLIT HEPARIN | Leadiant Biosciences SA (CH) | 2018-10-17 | — | — | EP | disclosed |
| WO-2018177860-A1 | 2-(4-(4-(BROMO-METHOXYBENZAMIDO)BENZYLAMINO)PHENYL)BENZAZOLE DERIVATIVES AND THEIR USE AS ANTI-HEPARANASE | LEADIANT BIOSCIENCES SA IN LIQUIDAZIONE (CH) | 2018-10-04 | — | — | WO | disclosed |
| WO-2018177863-A1 | DERIVATIVES OF THE DISODIUM 2,2'-{CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(1-METHYL-1H-PYRROLE-4,2-DIYL) CARBONYLIMINO]}DINAPHTHALENE-1,5-DISULFONATE SALT AND RELATED COMPOUNDS AS HEPARANASE INHIBITORS FOR THE TREATMENT OF CANCER | LEADIANT BIOSCIENCES SA IN LIQUIDAZIONE (CH) | 2018-10-04 | — | — | WO | disclosed |
| US-5728717-A | COGNITION ACTIVATORS, ANTIDEPRESSANTS | HOECHST MARION ROUSSEL INC. (US) | 1998-03-17 | — | — | US | disclosed |
| US-5668154-A | TREATMENT OF MEMORY DYSFUNCTION, ALZHEIMER*S DISEASE, ANTIDEPRESSANTS | HOECHST MARION ROUSSEL INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996039405-A1 | PYRIDINIMINYL-1,2-BENZISOXAZOLES AND- BENZISOTHIAZOLES AS ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-12-12 | — | — | WO | disclosed |
| EP-0717638-A1 | IMPROVED PHARMACEUTICAL FORMULATION | SUPERGEN, INC. (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5494908-A | ANTIDEPRESSANT | HOECHST-ROUSSEL PHARMACEUTICAL INCORPORATED (US) | 1996-02-27 | — | — | US | disclosed |
| WO-1995006485-A1 | IMPROVED PHARMACEUTICAL FORMULATION | SUPERGEN, INC. (US) | 1995-03-09 | — | — | WO | disclosed |
| EP-0586585-A4 | — | — | 1994-08-31 | — | — | EP | disclosed |
| EP-0583161-A2 | 4-Aminopyrrole-2-carboxamide derivatives as antiviral agents | PHARMACIA S.p.A. (IT) | 1994-02-16 | — | — | EP | disclosed |
| EP-0550518-A1 | 1-SUBSTITUTED PHENOXATHIIN DERIVATIVES AS ANTIDEPRESSANTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1988002370-A1 | 2-SUBSTITUTED-E-FUSED-[1,2,4]TRIAZOLO[1,5-C]PYRIMIDINES PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | CIBA-GEIGY AG (CH) | 1988-04-07 | — | — | WO | disclosed |