Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.67 |
| ▸ | ERN1 | O75460 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23110040 | 0.85 | MEN1 (0.67) | HPGDSERN1MEN1POLBRAB9A | |
| SCHEMBL2083801 | 0.83 | MEN1 (0.72) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL15293613 | 0.81 | ESR1 (0.60) | HPGDSERN1MEN1POLBRAB9A | |
| SCHEMBL3639170 | 0.80 | HPGDS (1.00) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL14156943 | 0.80 | MEN1 (0.68) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL13335785 | 0.78 | HSD17B1 (0.70) | HPGDSHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL1289509 | 0.77 | ESR1 (0.51) | HPGDSERN1MEN1POLBRAB9A | |
| SCHEMBL22068905 | 0.77 | POLB (0.68) | HPGDSERN1MEN1POLBRAB9A | |
| SCHEMBL5226359 | 0.76 | APP (0.53) | HPGDSHSD17B1HSD17B2ESR1ESR2 | |
| SCHEMBL6378961 | 0.76 | RARB (0.61) | HPGDSERN1MEN1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202772-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RIBOSOME INACTIVATING PROTEINS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202772-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RIBOSOME INACTIVATING PROTEINS | RACK1, RRBP1, RPL30 | HPGDS 3257/4885ERN1 326/4885MEN1 4218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.