SCHEMBL2457365

SCHEMBL2457365

c1ccc(-c2ccc3[nH]cnc3c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 4/20 0.50
QPCTL Q9NXS2 2/20 0.50
NPC1 O15118 3/20 0.47
SMN1; SMN2 Q16637 4/20 0.45
RAB9A P51151 3/20 0.45
MAPT P10636 3/20 0.45
DYRK3 O43781 1/20 0.44
CLK1 P49759 1/20 0.44
CLK2 P49760 1/20 0.44
CLK3 P49761 1/20 0.44
GSK3B P49841 1/20 0.44
CDK5 Q00535 1/20 0.44
DYRK1A Q13627 1/20 0.44
CDK5R1 Q15078 1/20 0.44
DYRK2 Q92630 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
JAK2 O60674 1/20 0.43
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28190280 0.96 QPCT (0.47) QPCTQPCTLNPC1SMN1; SMN2RAB9A
SCHEMBL22418755 0.96 QPCT (0.47) QPCTQPCTLNPC1SMN1; SMN2RAB9A
SCHEMBL31143361 0.90 MAPT (0.50) QPCTQPCTLNPC1SMN1; SMN2RAB9A
SCHEMBL6008269 0.90 MAPT (0.50) QPCTQPCTLNPC1SMN1; SMN2RAB9A
SCHEMBL14669372 0.86 NPC1 (0.49) NPC1SMN1; SMN2RAB9AMAPTKDM4E
SCHEMBL2462345 0.85 QPCT (0.68) QPCTQPCTLNPC1SMN1; SMN2RAB9A
SCHEMBL459808 0.84 NPC1 (0.54) NPC1SMN1; SMN2RAB9AMAPTKDM4E
SCHEMBL13373486 0.83 PARP1 (0.46) QPCTQPCTLMAPTKDM4EALDH1A1
SCHEMBL7021134 0.83 QPCT (0.49) QPCTQPCTLMAPTCLK1CLK2
SCHEMBL28178021 0.83 PARP1 (0.46) QPCTQPCTLMAPTCDK5CDK5R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466920-A Organic compound for light-emitting device, application of organic compound and organic electroluminescent device 合肥鼎材科技有限公司 2024-01-30 CN disclosed
EP-3727797-B1 A HYBRID PHOTOPOLYMER COMPOSITION FOR ADDITIVE MANUFACTURING PERSTORP AB (SE) 2023-09-27 EP disclosed
CN-115701969-A Novel encapsulated cosmetic compositions and uses thereof ELC管理有限责任公司 2023-02-14 CN disclosed
CN-111491776-B Hybrid photopolymer compositions for additive manufacturing 佩什托普公司 2022-06-03 CN disclosed
CN-108610345-B Synthesis method of benzimidazole [1,2-c ] quinazoline compound 河南大学 2021-03-30 CN disclosed
CN-108610345-A A kind of synthetic method of benzimidazole [1,2-c] quinazoline compounds 河南大学 2018-10-02 CN disclosed
CN-108191870-A For benzimidazole simultaneously [1,2-A] benzimidizole derivatives of electronic application UDC 爱尔兰有限责任公司 2018-06-22 CN disclosed
CN-104395316-B Benzimidazo [1,2-A ] benzimidazole derivatives for electronic applications UDC 爱尔兰有限责任公司 2018-01-19 CN disclosed
CN-107353289-A Benzimidazole for electronic application simultaneously [1,2 A] benzimidizole derivatives UDC 爱尔兰有限责任公司 2017-11-17 CN disclosed
US-9780310-B2 Heterocyclic compound for organic electroluminescent device and its application TOSOH CORPORATION (JP) 2017-10-03 US disclosed
EP-0407554-A4 METALLIC OXIDE-OXIRANE POLYMERS AND PREPOLYMERS 1992-10-21 EP disclosed
US-5026816-A Reaction product of diglycidyl ether of (bisphenol a or resorcinol) with metallic oxide in presence of imidazole catalyst KEEHAN DONALD J (US) 1991-06-25 US disclosed
EP-0407554-A1 METALLIC OXIDE-OXIRANE POLYMERS AND PREPOLYMERS. KEEHAN DONALD J (US) 1991-01-16 EP disclosed
WO-1990008168-A1 METALLIC OXIDE-OXIRANE POLYMERS AND PREPOLYMERS KEEHAN DONALD J (US) 1990-07-26 WO disclosed
US-4880892-A PHOSPHONIUM OR PHOSPHORANE CATALYST, PROTECTIVE COATINGS CIBA-GEIGY CORPORATION (US) 1989-11-14 US disclosed
US-4375508-A ACETHYLENIC HYDROCARBON CHAIN EASTMAN KODAK COMPANY (US) 1983-03-01 US disclosed
US-4283488-A SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1981-08-11 US disclosed
US-4108667-A Photographic compositions and elements containing benzo[a]quinolizinium methine dyes EASTMAN KODAK COMPANY (US) 1978-08-22 US disclosed
US-4080207-A Radiation-sensitive compositions and photographic elements containing N-(acylhydrazinophenyl) thioamide nucleating agents EASTMAN KODAK COMPANY (US) 1978-03-21 US disclosed
US-4003750-A METHINE DYES EASTMAN KODAK COMPANY (US) 1977-01-18 US disclosed