Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.51 |
| ▸ | IL1B | P01584 | 4/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24575109 | 0.89 | NLRP3 (0.45) | NLRP3IL1BTNF | |
| SCHEMBL24575108 | 0.89 | NLRP3 (0.43) | NLRP3IL1BTNF | |
| SCHEMBL30108846 | 0.82 | NLRP3 (0.51) | NLRP3IL1BTNF | |
| SCHEMBL25857019 | 0.82 | NLRP3 (0.51) | NLRP3IL1BTNF | |
| SCHEMBL28934678 | 0.82 | NLRP3 (0.51) | NLRP3IL1BTNF | |
| SCHEMBL24575339 | 0.78 | IL1B (0.41) | NLRP3IL1BTNF | |
| SCHEMBL31681939 | 0.72 | IL1B (0.38) | NLRP3IL1BTNF | |
| SCHEMBL24574823 | 0.72 | MAPT (0.48) | NLRP3IL1BTNF | |
| SCHEMBL28934454 | 0.72 | MAPT (0.48) | NLRP3IL1BTNF | |
| SCHEMBL25861226 | 0.72 | MAPT (0.48) | NLRP3IL1BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135567-A1 | PYRIDAZINE-CONTAINING COMPOUND AND MEDICINAL USE THEREOF | 上海拓界生物医药科技有限公司 | 2022-06-30 | — | — | WO | disclosed |