SCHEMBL24575640

SCHEMBL24575640

O=c1ccn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2OP(=O)(O)O)c(=O)[nH]1

nearest known ligand 0.80

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 7/20 0.67
P2RY2 P41231 9/20 0.66
P2RY4 P51582 5/20 0.66
P2RY14 Q15391 5/20 0.64
RNASEL Q05823 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7034690 0.91 P2RY6 (0.67) P2RY6P2RY2P2RY4P2RY14
SCHEMBL7034697 0.91 P2RY6 (0.67) P2RY6P2RY2P2RY4P2RY14
SCHEMBL1230623 0.91 P2RY6 (0.60) P2RY6P2RY2P2RY4P2RY14
SCHEMBL20769287 0.90 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL2056722 0.90 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL842952 0.90 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL600248 0.90 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL20769292 0.90 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL20769289 0.90 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL10959520 0.90 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220205009-A1 MUTATED tRNA FOR CODON EXPANSION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-06-30 US disclosed