SCHEMBL600248

SCHEMBL600248

CO[C@@H]1[C@H](O)[C@@H](COP(=O)(O)O)O[C@H]1n1ccc(=O)[nH]c1=O

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 8/20 0.66
P2RY2 P41231 11/20 0.64
P2RY4 P51582 7/20 0.64
P2RY14 Q15391 6/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10959520 1.00 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL20769287 1.00 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL2056722 1.00 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL28920904 0.94 P2RY6 (0.72) P2RY6P2RY2P2RY4P2RY14
SCHEMBL22389513 0.93 P2RY2 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL25388253 0.92 P2RY6 (0.63) P2RY6P2RY2P2RY4P2RY14
SCHEMBL18126746 0.91 P2RY6 (0.59) P2RY6P2RY2P2RY4P2RY14
SCHEMBL19546708 0.91 P2RY6 (0.59) P2RY6P2RY2P2RY4P2RY14
SCHEMBL24043084 0.91 P2RY6 (0.59) P2RY6P2RY2P2RY4P2RY14
SCHEMBL19862754 0.91 P2RY6 (0.59) P2RY6P2RY2P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745239-A1 CFB INHIBITOR COMPOSITION AND USE THEREOF Rigerna Therapeutics Co., Ltd. (CN) 2026-05-20 EP claimed
WO-2025031301-A1 FTO INHIBITOR COMPOSITION AND USE THEREOF 苏州炫景生物科技有限公司 2025-02-13 WO claimed
WO-2025026228-A1 CFB INHIBITOR COMPOSITION AND USE THEREOF 苏州炫景生物科技有限公司 2025-02-06 WO claimed
WO-2024027809-A1 RNA INHIBITOR FOR INHIBITING APOC3 GENE EXPRESSION AND USE THEREOF 厦门甘宝利生物医药有限公司 2024-02-08 WO claimed
US-11884919-B2 Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene ALNYLAM PHARMACEUTICALS, INC. (US) 2024-01-30 US claimed
US-20230304058-A1 NOVEL 5'CAP ANALOG HAVING CAP2 STRUCTURE AND PREPARATION METHOD THEREFOR SHENZHEN RHEGEN BIOTECHNOLOGY CO., LTD. (CN) 2023-09-28 US claimed
WO-2023169548-A1 LPA INHIBITOR AND USE THEREOF 厦门甘宝利生物医药有限公司 2023-09-14 WO claimed
EP-4202053-A1 NOVEL 5'CAP ANALOG HAVING CAP2 STRUCTURE AND PREPARATION METHOD THEREFOR Shenzhen Rhegen Biotechnology Co., Ltd. (CN) 2023-06-28 EP claimed
US-20220243199-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF SERUM AMYLOID A GENE BANK OF AMERICA, N.A. 2022-08-04 US claimed
WO-2022036858-A1 NOVEL 5'CAP ANALOG HAVING CAP2 STRUCTURE AND PREPARATION METHOD THEREFOR 深圳市瑞吉生物科技有限公司 2022-02-24 WO claimed
US-20160194633-A1 Lipid Formulated Compositions and Methods for Inhibiting Expression of Serum Amyloid A Gene BANK OF AMERICA, N.A. 2016-07-07 US claimed
EP-2334793-B1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF SERUM AMYLOID A GENE ALNYLAM PHARMACEUTICALS INC (US) 2016-04-06 EP claimed
EP-2905336-A1 Compositions and methods for inhibiting expression of a gene from the ebola Alnylam Pharmaceuticals Inc. (US) 2015-08-12 EP claimed
EP-2589660-B1 Compositions and methods for inhibiting expression of a gene from the Ebola ALNYLAM PHARMACEUTICALS INC (US) 2014-11-26 EP claimed
EP-2147102-B1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF A GENE FROM THE EBOLA ALNYLAM PHARMACEUTICALS INC (US) 2014-01-15 EP claimed
EP-2589660-A1 Compositions and methods for inhibiting expression of a gene from the Ebola Alnylam Pharmaceuticals Inc. (US) 2013-05-08 EP claimed
EP-2334793-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF SERUM AMYLOID A GENE Alnylam Pharmaceuticals, Inc. (US) 2011-06-22 EP claimed
US-7846908-B2 RNAi modulation of TGF-beta and therapeutic uses thereof ALNYLAM PHARMACEUTICALS, INC. (US) 2010-12-07 US claimed
WO-2010036962-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF SERUM AMYLOID A GENE ALNYLAM PHARMACEUTICALS, INC. (US) 2010-04-01 WO claimed
US-4507089-A Mechanical support module for nucleic acid TCHUEMPE TCHUENTE GERMAIN (FR) 1985-03-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11884919-B2 Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene SAAL1, APOB, SCARB1 P2RY6 4176/4885P2RY2 4259/4885P2RY4 4616/4885
US-20230304058-A1 NOVEL 5'CAP ANALOG HAVING CAP2 STRUCTURE AND PREPARATION METHOD THEREFOR RNGTT, CAPG, CPSF7 P2RY6 2979/4885P2RY2 2207/4885P2RY4 3022/4885
US-20220243199-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF SERUM AMYLOID A GENE SAAL1, APOB, HNRNPAB P2RY6 4338/4885P2RY2 4349/4885P2RY4 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.