SCHEMBL842952

SCHEMBL842952

O=c1ccn([C@H]2O[C@@H](COP(=O)(O)O)C(O)C2OF)c(=O)[nH]1

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY6 Q15077 7/20 0.66
P2RY2 P41231 10/20 0.64
P2RY4 P51582 5/20 0.64
P2RY14 Q15391 6/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20769292 1.00 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL24575640 0.90 P2RY6 (0.67) P2RY6P2RY2P2RY4P2RY14
SCHEMBL4575896 0.90 P2RY2 (0.76) P2RY6P2RY2P2RY4P2RY14
SCHEMBL10959520 0.89 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL20769289 0.89 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL600248 0.89 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL20769287 0.89 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL2056722 0.89 P2RY6 (0.66) P2RY6P2RY2P2RY4P2RY14
SCHEMBL13834782 0.89 P2RY6 (0.81) P2RY6P2RY2P2RY4P2RY14
SCHEMBL8091045 0.89 P2RY6 (0.81) P2RY6P2RY2P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024027809-A1 RNA INHIBITOR FOR INHIBITING APOC3 GENE EXPRESSION AND USE THEREOF 厦门甘宝利生物医药有限公司 2024-02-08 WO claimed
WO-2023169548-A1 LPA INHIBITOR AND USE THEREOF 厦门甘宝利生物医药有限公司 2023-09-14 WO claimed
JP-2007501615-A 2007-02-01 JP claimed
EP-1654362-A2 5'-AND 3'-CAPPED APTAMERS AND USES THEREFOR EYETECH PHARMACEUTICALS, INC. (US) 2006-05-10 EP claimed
US-20050096290-A1 5'-and 3'-capped aptamers and uses therefor (OSI) EYETECH, INC. 2005-05-05 US claimed
WO-2005014814-A2 5’-AND 3’-CAPPED APTAMERS AND USES THEREFOR (OSI) EYETECH, INC. (US) 2005-02-17 WO claimed
WO-2024088190-A1 RNA INHIBITOR FOR INHIBITING LPA GENE EXPRESSION AND USE THEREOF 厦门甘宝利生物医药有限公司 2024-05-02 WO disclosed
WO-2024027809-A1 RNA INHIBITOR FOR INHIBITING APOC3 GENE EXPRESSION AND USE THEREOF 厦门甘宝利生物医药有限公司 2024-02-08 WO disclosed
US-11840691-B2 Compound and application thereof KYLONOVA (XIAMEN) BIOPHARMA CO., LTD. (CN) 2023-12-12 US disclosed
US-20230374513-A1 NOVEL COMPOUND AND APPLICATION THEREOF KYLONOVA (XIAMEN) BIOPHARMA CO., LTD. (CN) 2023-11-23 US disclosed
WO-2023169548-A1 LPA INHIBITOR AND USE THEREOF 厦门甘宝利生物医药有限公司 2023-09-14 WO disclosed
US-20230110095-A1 NOVEL COMPOUND AND APPLICATION THEREOF HANGZHOU HYGIEIA PHARMACEUTICAL CO., LTD. (CN) 2023-04-13 US disclosed
US-20230013636-A1 EXOSOMES-BASED THERAPY FOR LIVER FIBROSIS AND OTHER DISEASES WITH FIBROSIS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-01-19 US disclosed
US-20050260153-A1 Facilitation of iontophoresis using charged moieties OLDTECH, INC. 2005-11-24 US disclosed
US-20050260651-A1 Enhanced biologically active conjugates OLDTECH, INC. 2005-11-24 US disclosed
WO-2005110489-A2 NUCLEIC ACID APTAMERS CONJUGATED TO HIGH MOLECULAR WEIGHT STERIC GROUPS (OSI) EYETECH, INC. (US) 2005-11-24 WO disclosed
US-20050096257-A1 Administering platelet derived growth factor antagonist and endothelial growth factor antagonist OPHTHOTECH CORPORATION 2005-05-05 US disclosed
US-20050096290-A1 5'-and 3'-capped aptamers and uses therefor (OSI) EYETECH, INC. 2005-05-05 US disclosed
WO-2005020972-A2 COMBINATION THERAPY FOR THE TREATMENT OF OCULAR NEOVASCULAR DISORDERS (OSI) EYETECH, INC. (US) 2005-03-10 WO disclosed
WO-2005014814-A2 5’-AND 3’-CAPPED APTAMERS AND USES THEREFOR (OSI) EYETECH, INC. (US) 2005-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230374513-A1 NOVEL COMPOUND AND APPLICATION THEREOF GALNT6, GALNT3, GALNT14 P2RY6 4473/4885P2RY2 4752/4885P2RY4 4709/4885
US-20230110095-A1 NOVEL COMPOUND AND APPLICATION THEREOF GALNT6, GALNT3, GALNT14 P2RY6 4473/4885P2RY2 4752/4885P2RY4 4709/4885
US-20050096290-A1 5'-and 3'-capped aptamers and uses therefor FLT4, TEK, FLT1 P2RY6 1295/4885P2RY2 1820/4885P2RY4 984/4885
US-11840691-B2 Compound and application thereof GALNT6, GALNT3, GALNT14 P2RY6 4537/4885P2RY2 4804/4885P2RY4 4744/4885
US-20050260153-A1 Facilitation of iontophoresis using charged moieties ANXA11, SLC7A1, TRPC6 P2RY6 218/4885P2RY2 307/4885P2RY4 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.