Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 12/20 | 0.71 |
| ▸ | NLRP3 | Q96P20 | 14/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480331 | 0.98 | IL1B (0.71) | IL1BNLRP3 | |
| SCHEMBL24575060 | 0.98 | IL1B (0.71) | IL1BNLRP3 | |
| SCHEMBL29027408 | 0.98 | IL1B (0.71) | IL1BNLRP3 | |
| SCHEMBL26772269 | 0.89 | IL1B (0.77) | IL1BNLRP3 | |
| SCHEMBL29027409 | 0.87 | NLRP3 (0.69) | IL1BNLRP3 | |
| SCHEMBL24575347 | 0.87 | NLRP3 (0.69) | IL1BNLRP3 | |
| SCHEMBL30480330 | 0.87 | NLRP3 (0.69) | IL1BNLRP3 | |
| SCHEMBL26772249 | 0.86 | IL1B (0.73) | IL1BNLRP3 | |
| SCHEMBL24575305 | 0.85 | NLRP3 (0.75) | IL1BNLRP3 | |
| SCHEMBL29696876 | 0.85 | NLRP3 (0.75) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022135567-A1 | PYRIDAZINE-CONTAINING COMPOUND AND MEDICINAL USE THEREOF | 上海拓界生物医药科技有限公司 | 2022-06-30 | — | — | WO | disclosed |