Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24577155 | 0.81 | IKBKE (0.34) | KMT2AMEN1 | |
| SCHEMBL24577993 | 0.80 | MAPT (0.31) | — | |
| SCHEMBL24577132 | 0.80 | NAMPT (0.38) | KMT2AMEN1 | |
| SCHEMBL24577112 | 0.80 | HDAC6 (0.34) | — | |
| SCHEMBL24579097 | 0.76 | HDAC6 (0.36) | KMT2AMEN1 | |
| SCHEMBL24578879 | 0.76 | PDE3B (0.33) | — | |
| SCHEMBL24577174 | 0.76 | IKBKE (0.38) | — | |
| SCHEMBL24578874 | 0.75 | IKBKE (0.40) | — | |
| SCHEMBL24579014 | 0.74 | — | — | |
| SCHEMBL24577681 | 0.74 | KDM4E (0.34) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136509-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2022-06-30 | — | — | WO | disclosed |